Lifeboat Foundation

Influential inventions often combine existing tools in new ways. The iPhone, for instance, amalgamated the telephone, web browser and camera, among many other devices.

The same is now possible in gene editing. Rather than employ separate tools for editing genes and regulating their expression, these distinct goals can now be combined into a single tool that can simultaneously and independently address different genetic diseases in the same cell.

In a new paper in Nature Communications, researchers in the Center for Precision Engineering for Health (CPE4H) at the University of Pennsylvania School of Engineering and Applied Science (Penn Engineering) describe minimal versatile genetic perturbation technology (mvGPT).

An international research team, working with cutting-edge technology at the University of Nebraska–Lincoln, has made a discovery that may dramatically expand the materials used in next-generation, energy-efficient memory and logic devices.

The team, which includes Nebraska’s Abdelghani Laraoui, assistant professor of mechanical and materials engineering, successfully demonstrated for the first time the imaging of magnetic skyrmions at room temperature in composition engineered magnetic materials. The team observed the tiny, vortex-like particles in these magnetic materials using a nitrogen-vacancy scanning probe in Laraoui’s lab. The findings are published in ACS Nano.

“This discovery is a huge step forward because, until now, scientists could only observe these skyrmions in bulk chiral magnetic materials at very low temperatures,” Laraoui said. “Being able to study them at room temperature opens up a whole new world of applications and possibilities.”

Bimetallic particles, composed of a noble metal and a base metal, exhibit unique catalytic properties in selective heterogeneous hydrogenations due to their distinct geometric and electronic structures. At the molecular level, effective and selective hydrogenation requires site-specific interactions where the active atoms on the catalyst particle selectively engage with the functional group targeted for transformation in the substrate.

Reducing the particle to nanoscale atomic clusters and single-atom alloys enhances surface dispersion and improves the efficient utilization of noble metal atoms. These size reductions also simultaneously change the electronic structure of the active sites, which significantly impacts the intrinsic activity or product distributions.

By precisely tuning the bonding structures of noble metal single atoms with the base metal host, reactants are flexibly accommodated and the electronic properties are fine-tuned to activate specific functional groups. However, the fabrication of such atomically precise active sites remains a challenge.

How does the Earth generate its magnetic field? While the basic mechanisms seem to be understood, many details remain unresolved. A team of researchers from the Center for Advanced Systems Understanding at the Helmholtz-Zentrum Dresden-Rossendorf, Sandia National Laboratories (U.S.) and the French Alternative Energies and Atomic Energy Commission has introduced a simulation method that promises new insights into the Earth’s core.

The method, presented in the Proceedings of the National Academy of Sciences, simulates not only the behavior of atoms, but also the magnetic properties of materials. The approach is significant for geophysics and could support the development of neuromorphic computing—an approach to more efficient AI systems.

The Earth’s magnetic field is essential for sustaining life, as it shields the planet from cosmic radiation and solar wind. It is generated by the geodynamo effect. “We know that the Earth’s core is primarily composed of iron,” explains Attila Cangi, Head of the Machine Learning for Materials Design department at CASUS.

In a world grappling with a multitude of health threats—ranging from fast-spreading viruses to chronic diseases and drug-resistant bacteria—the need for quick, reliable, and easy-to-use home diagnostic tests has never been greater. Imagine a future where these tests can be done anywhere, by anyone, using a device as small and portable as your smartwatch. To do that, you need microchips capable of detecting miniscule concentrations of viruses or bacteria in the air.

Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect our risk—in opposite directions—for developing colon cancer.

The link between these bile acids and colon cancer risk was recently uncovered as University of Wisconsin–Madison scientists sought to better understand the relationship between gut microbes and our bodies.

In many ways, that relationship revolves around a specific protein called the farnesoid X receptor, or FXR, which helps maintain a healthy gut through its intimate relationship with bile acids. FXR controls the production of bile acids in the liver, but it also responds in different ways to the presence of various bile acids that microbes have modified.

A German startup is pioneering remote driving technology, offering a unique alternative to autonomous vehicles. By utilizing human drivers operating from remote locations, the company provides cost-effective rides and vehicle delivery services. This innovative approach is gaining traction, with a growing fleet and thousands of completed rides.

In 2025, we’ll see more AI agents entering the workforce, transforming workflows by simplifying, enhancing, and automating tasks across industries.

Dive into the mesmerizing world of quantum mechanics and uncover the secrets of the quantum vacuum—a concept that challenges everything we thought we knew about empty space. This video explores the dynamic, energy-filled realm of the quantum vacuum, where virtual particles pop in and out of existence and Zero Point Energy offers tantalizing possibilities for clean, limitless power.

Learn about the Casimir Effect, a fascinating phenomenon where quantum fluctuations create forces between metal plates, and discover how these principles could revolutionize fields like nanotechnology, energy production, and even space exploration. From the Heisenberg Uncertainty Principle to the Reverse Casimir Effect, this journey into quantum mechanics highlights the incredible potential of harnessing Zero Point Energy for a sustainable future.

Continue reading “Hidden Energy in Empty Space: Casimir Effect and Zero Point Energy” »

LLMs use “Bag of Heuristics” to do approximate retrieval.