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Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering clues for future RNA-based treatments and how the body tells “self” from “nonself.” Not everything inside us is, strictly speaking, part of us. The closer we examine the genome, the more we co

As you age you naturally lose neurons and muscle mass and experience a decline in fertility and wound healing ability. Previous research in animals has offered several potential techniques for turning back the biological clock in specific tissues, including exercise and calorie restriction. However, age reversal of blood cells or at whole organism level has so far been elusive.

Discover how CERN’s research into quantum fields could revolutionize our understanding of gravity! This deep dive explores the theoretical possibilities of manipulating quantum fields and their potential connection to gravitational forces. From Einstein’s predictions to cutting-edge experiments at the Large Hadron Collider, we examine what’s really happening at the frontier of physics research.

Learn how quantum gravity research could potentially transform:

Space travel and propulsion systems 🚀

Revolutionary energy production ⚡

Medical applications and treatments 🏥

Japanese researchers are making groundbreaking discoveries on the mechanisms of aging and working to apply them. As we age, senescent cells, or aged cells that have stopped dividing, accumulate, causing inflammation that can damage blood vessels and organs. Animal experiments have shown that removing these cells improves kidney function and reduces arteriosclerosis. They have led to the identification of a drug and development of a vaccine to eliminate the cells.

Disrupted sleep-wake and molecular circadian rhythms are a feature of aging associated with metabolic disease and reduced levels of NAD+, yet whether changes in nucleotide metabolism control circadian behavioral and genomic rhythms remains unknown. Here, we reveal that supplementation with the NAD + precursor nicotinamide riboside (NR) markedly reprograms metabolic and stress-response pathways that decline with aging through inhibition of the clock repressor PER2. NR enhances BMAL1 chromatin binding genome-wide through PER2 K680 deacetylation, which in turn primes PER2 phosphorylation within a domain that controls nuclear transport and stability and that is mutated in human advanced sleep phase syndrome.

Astronomers at the University of Warwick have made an exciting discovery—a rare, high-mass compact binary star system located just 150 light-years away in the Milky Way. This marks the first time such a system has been observed, offering valuable insights into the origins of type 1a supernovae.

Astronomers have confirmed a pair of white dwarfs on a collision course to become a type 1a supernova—the brightest cosmic explosion. This system, the heaviest of its kind ever identified, has a combined mass of 1.56 times that of the sun.

Separated by only 1/60th of the Earth-sun distance, the stars currently orbit each other in just over 14 hours. However, gravitational wave radiation will gradually draw them closer over billions of years. On the verge of their explosive end, the stars will orbit so rapidly that a single orbit will take only 30–40 seconds.