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The adeno-associated viruses often used as vectors to deliver gene therapy can trigger unwanted and sometimes dangerous immune responses. Now, a Harvard University team led by renowned geneticist George Church, Ph.D., has developed a way to “cloak” AAVs from immune surveillance. They’ve spun off Ally Therapeutics to develop it.

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NASA has decided to launch the multibillion-dollar Europa Clipper mission on a commercial heavy-lift rocket in October 2024, and not on the government-owned Space Launch System, officials said Wednesday.

The decision ends a prolonged dilemma for NASA, which until last year was legally required to launch the Europa Clipper mission on the more expensive Space Launch System. The language passed in previous NASA appropriations bills directed NASA to launch the probe on the SLS rocket, but Congress relented in the fiscal year 2021 spending bill passed in December.

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Stimuli-responsive control of drug activation can mitigate issues caused by poor drug selectivity. Now, it has been shown that mechanical force—induced by ultrasound—can be used to activate drugs in three different systems. This approach has enabled the activation of antibiotics or a cytotoxic anticancer agent from synthetic polymers, polyaptamers and nanoparticle assemblies.