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MIT study sheds light on the longstanding question of why cancer cells get their energy from fermentation.

In the 1920s, German chemist Otto Warburg discovered that cancer cells don’t metabolize sugar the same way that healthy cells usually do. Since then, scientists have tried to figure out why cancer cells use this alternative pathway, which is much less efficient.

MIT biologists have now found a possible answer to this longstanding question. In a study appearing in Molecular Cell, they showed that this metabolic pathway, known as fermentation, helps cells to regenerate large quantities of a molecule called NAD+, which they need to synthesize DNA and other important molecules. Their findings also account for why other types of rapidly proliferating cells, such as immune cells, switch over to fermentation.

A mitochondrial hormone expressed by cells deep in the brain appears to play a role in improving metabolism and fighting off obesity, according to a new study in mice.

A new study on the rotation of the universe’s first light could suggest physicists need new rule-breaking subatomic particles.

For noted theoretical physicist Frank Wilczek, finding aliens is a matter of figuring out what exactly we are looking for. To detect other space civilizations, we need to search for the specific effects they might be having on their worlds, argues the Nobel laureate in a new proposal.

Writing in the Wall Street Journal, Wilczek says that it’s a real challenge to figure out which among the over 4000 exoplanets that we found so far outside of our solar system might host extraterrestrial life. The classic way of listening for space signals is insufficient and inefficient, says the scientist. What might really help are new developments in exoplanetary astronomy that can allow us to get much more precise information about faraway space objects.

In particular, there are two ways we should focus our attention to turn the odds of finding alien life in our favor, argues the physicist.

Formic ventures — taking on huge challenges — from virtual reality technologist to longevity biotechnology investor.

Michael Antonov is the Founder and CEO of The Michael Antonov Foundation (https://antonovfoundation.org/), a charitable organization that supports biotechnology research and various causes that improve well being of people around the world, as well as Formic Ventures (https://formic.vc/index.html), an early stage high tech and biotech investment firm focused on prolonging human healthspan and empowering human creativity.

Continue reading “Michael Antonov — Formic Ventures — Taking On Huge Challenges — From VR To Longevity Biotechnology” »

A type of novel molecular voltage sensor makes it possible to watch nerve cells at work. The principle of the method has been known for some time. However, researchers at the University of Bonn and the University of California in Los Angeles have now succeeded in significantly improving it. It allows the propagation of electrical signals in living nerve cells to be observed with high temporal and spatial resolution. This enables investigations into completely new questions that were previously closed to research. The study has now been published in the journal PNAS.

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Elon Musk says the Tesla Roadster will be able to fly a little bit, so perhaps the new Model S yoke will be used so that the driver pulls back on it to fly.

It is the OEC biggest challenge.

Google’s parent, Alphabet, has waded through one controversy after another involving its top researchers and executives in the field over the past 18 months.