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Sep 15, 2020

The human story of how ventilators came to breathe for us

Posted by in categories: biotech/medical, ethics

Medical Ethics and “Futility” (Note: Listen here function)


We breathe about 12 to 20 times a minute, without having to think. Inhale: and air flows through the mouth and nose, into the trachea. The bronchi stem out like a wishbone, and keep branching, dividing and dividing, and finally feeding out into the tiny air sacs of alveoli. Capillaries – blood vessels thinner than hairs – twine around each alveolus. Both the air sac and the blood vessel are tiny, delicate, one cell thick: portals where blood (the atmosphere of the body) meets air (atmosphere of the world). Oxygen passes from air to blood; carbon dioxide, from blood to air. Then, the exhale pushes that carbon dioxide back out the mouth and nose. Capillaries channel newly oxygenated blood back to the heart. That oxygen fuels the body. That’s why we breathe.

Today, these basics of human respiration and metabolism feel obvious – and ventilators, the machines that breathe for sick people, do, too. We have so many medical devices, so of course we’d need, and have, machines that help us to breathe. But there’s a strange, and deeply human, story behind how we learned to breathe for each other. It starts long ago, when we didn’t understand breathing at all. When the body’s failure to breathe was incomprehensible, incurable, and fatal. When we had no way of knowing how badly we needed ventilators to keep people alive through those moments of vulnerability, lest those moments be their last.

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Sep 15, 2020

Dr. Brian Kennedy — Preventive Medicine in an Aging Society

Posted by in categories: biotech/medical, life extension

At our first online conference, Ending Age-Related Diseases 2020, Dr. Brian Kennedy of the National University of Singapore discussed the aging population of Singapore, the need for comprehensive healthcare, alpha-ketoglutarate and its effects against frailty in mice, ongoing trials of ketoglutarate in humans, spermidine against obesity, the role of biomarkers, and the importance of keeping people well rather than simply treating them when they are sick.

Sep 15, 2020

Honda Unveils Its First Electric Car For Japan

Posted by in categories: sustainability, transportation

Honda Motor has unveiled its first electric vehicle for the Japanese market.

Sep 15, 2020

Venus Life Is Still A Longshot

Posted by in categories: alien life, evolution

Venus is suddenly a new hotspot for astrobiology, but its real value may be in what it teaches us about the evolution of life on our own planet.

Sep 15, 2020

Ageing Can Be A Thing Of The Past

Posted by in category: life extension

#aubreydegrey #ageing #ucaststudios #thetalkspot

The Talk Spot is an interview show where we have guests from all backgrounds on. This episode features returning guest Aubrey de Grey.

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Sep 14, 2020

General Atomics unveils ‘ultra-long endurance’ replacement for MQ-9 Reaper

Posted by in categories: military, robotics/AI, surveillance

General Atomics Aeronautical Systems has unveiled a rendering of its next-generation intelligence, surveillance and reconnaissance and strike unmanned air vehicle as a proposed replacement of the US Air Force’s MQ-9A Reaper.

Sep 14, 2020

Nvidia will keep ARM licensing “neutral,” wants to license GPU tech, too

Posted by in category: computing

But can Nvidia play nice with Apple, Linux, and other ARM partners?

Sep 14, 2020

Quantum startup CEO suggests we are only five years away from a quantum desktop computer

Posted by in categories: computing, quantum physics

Today at TechCrunch Disrupt 2020, leaders from three quantum computing startups joined TechCrunch editor Frederic Lardinois to discuss the future of the technology. IonQ CEO and president Peter Chapman suggested we could be as little as five years away from a desktop quantum computer, but not everyone agreed on that optimistic timeline.

“I think within the next several years, five years or so, you’ll start to see [desktop quantum machines]. Our goal is to get to a rack-mounted quantum computer,” Chapman said.

But that seemed a tad optimistic to Alan Baratz, CEO at D-Wave Systems. He says that when it comes to developing the super-conducting technology that his company is building, it requires a special kind of rather large quantum refrigeration unit called a dilution fridge, and that unit would make a five-year goal of having a desktop quantum PC highly unlikely.

Sep 14, 2020

Army COVID-19 vaccine may produce a side benefit: Cure for the common cold

Posted by in category: biotech/medical

Walter Reed researchers say based on what they’ve learned about COVID so far, you need to get a flu shot.


Scientists leading the Army’s coronavirus vaccine effort say this year’s flu shot is critical because they do not yet know whether getting the flu will make it likelier someone catches COVID-19.

Sep 14, 2020

New Map Charts Genetic Expression Across Tissue Types, Sexes

Posted by in categories: biotech/medical, genetics, life extension, neuroscience, sex

From the data, the GTEx team could identify the relationship between specific genes and a type of regulatory DNA called expression quantitative trait loci, or eQTL. At least one eQTL regulates almost every human gene, and each eQTL can regulate more than one gene, influencing expression, GTEx member and human geneticist Kristin Ardlie of the Broad Institute tells Science.

Another major takeaway from the analyses was that sex affected gene expression in almost all of the tissue types, from heart to lung to brain cells. “The vast majority of biology is shared by males and females,” yet the gene expression differences are vast and might explain differences in disease progression, GTEx study coauthor Barbara Stranger of Northwestern University’s Feinberg School of Medicine tells Science. “In the future, this knowledge may contribute to personalized medicine, where we consider biological sex as one of the relevant components of an individual’s characteristics,” she says in a statement issued by the Centre for Genome Regulation in Barcelona, where some of the researchers who participated in the GTEx project work.

Another of the studies bolsters the association between telomere length, ancestry, and aging. Telomere length is typically measured in blood cells; GTEx researchers examined it in 23 different tissue types and found blood is indeed a good proxy for overall length in other tissues. The team also showed that, as previously reported, shorter telomeres were associated with aging and longer ones were found in people of African ancestry. But not all earlier results held; the authors didn’t see a pattern of longer telomeres in females or constantly shorter telomeres across the tissues of smokers as previous studies had.

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