Lifeboat Foundation

Women with Alzheimer’s disease tend to live longer than men with the disease — and a new study suggests that a gene on the X chromosome may help explain why.

Each person typically has one pair of sex chromosomes in each cell of their body. People assigned female at birth typically have two X chromosomes, while people assigned male at birth typically have one X chromosome and one Y chromosome.

Researchers say a gene called KDM6A may explain why women with Alzheimer’s disease tend to live longer than men with the same condition.

Back in July, OpenAI’s latest language model, GPT-3, dazzled with its ability to churn out paragraphs that look as if they could have been written by a human. People started showing off how GPT-3 could also autocomplete code or fill in blanks in spreadsheets.

In one example, Twitter employee Paul Katsen tweeted “the spreadsheet function to rule them all,” in which GPT-3 fills out columns by itself, pulling in data for US states: the population of Michigan is 10.3 million, Alaska became a state in 1906, and so on.

Except that GPT-3 can be a bit of a bullshitter. The population of Michigan has never been 10.3 million, and Alaska became a state in 1959.

Simulating chemical processes is one of the most promising applications of quantum computers, but problems with noise have prevented nascent quantum systems from outperforming conventional computers on such tasks. Now, researchers at Google have taken a major step towards this goal by using the most powerful quantum computer yet built to successfully implement a protocol for calculating the electronic structure of a molecule. The results may form a blueprint for complex, useful calculations on quantum computers affected by noise.

In October 2019, Google announced to great fanfare that its 53-qubit Sycamore computer had achieved quantum advantage. This means that a quantum computer can solve at least one problem much faster than any conventional supercomputer. However, Google researchers openly acknowledged that the problem Sycamore solved (sampling the outcome of a random quantum circuit) is easy for a quantum computer but difficult for a conventional supercomputer — and had little practical use.

What researchers would really like to do is use quantum computers to solve useful problems more effectively than possible with conventional computers: “Sycamore is extremely programmable and, in principle, you really can run any algorithm on it…In this sense, it’s a universal quantum computer,” explains team member Ryan Babbush of Google Research, “However, there’s a heavy caveat: there’s still noise affecting the device and as a result we’re still limited in the size of circuit we can implement.” Such noise, which results from classical sources such as thermal interference, can destroy the fragile superpositions crucial to quantum computation: “We can implement a completely universal circuit before the noise catches up and eventually destroys the computation,” says Babbush.

To overcome preexisting immunity that cripples the adenovirus vectors used in gene therapy and vaccines, scientists at the University of Pittsburgh created a CRISPR-based system that briefly suppresses the genes that cause the problem. The method improved gene therapy uptake in mice and is being developed by startup SafeGen.

A 16-m- (52.5-foot) long megalodon had a head 4.65 m (15.3 feet) long, a dorsal fin 1.62 m (5.3 feet) tall and a tail 3.85 m (9.4 feet) high, according to a study led by researchers from the University of Bristol and Swansea University.

The lockdown “cure” for COVID may have caused more damage than the disease…

We can print houses now. And windmills. And swimming pools.

This Video Explains The DNA Double Strand Breaks And Homologous Recombination (HR) Repair System Versus Non-homologous End-Joining (NHEJ)

Featured Image Source: SpaceX

Chief Engineer Elon Musk founded SpaceX with the goal to enable humans to live on Mars. The aerospace company is developing its next-generation launch vehicle in South Texas at Boca Chica Beach. According to SpaceX, Starship will be the most powerful rocket in the world; It will be a 120-meter-tall, two-stage launch vehicle consisting of a spacecraft capable of carrying one hundred passengers, and a Super Heavy booster used to propel the craft out of Earth’s atmosphere.

During the Humans To Mars teleconference that took place on Tuesday, Musk said Starship’s Super Heavy “booster prototype one” will initiate construction “this week.” SpaceX Boca Chica teams are building multiple Starship prototypes at the assembly facility, where gigantic vehicle assembly buildings are taking shape to accommodate the massive stainless-steel rocket booster. – “Making a prototype of something is, I think, relatively easy,” he said, “But building the production system so that you can build ultimately hundreds or thousands of Starships, that’s the hard part.”