Lifeboat Foundation

Bonny Lemma. Originally published in the HIR Winter 2019 Issue.

Jennifer Lopez has one more industry to add to her illustrious résumé: molecular biology. In 2016, she was asked to be the executive producer of a new futuristic bio-crime drama for NBC called C.R.I.S.P.R. While that project is a work of science fiction, the CRISPR technology that it is based on is very real.

CRISPR, or Clustered Regularly Interspaced Short Palindromic Repeats, is not just a gene editing technique, but also a phenomenon that carries significant implications for the future of biotechnology. Therefore, the interactions between the countless players in this field and the objectives driving them are crucial to understanding of CRISPR and the promise it holds.

Could also be used for other viruses too.

Two new studies explain how each cell in the body embeds a code that may become active when a healthy cell mutates into a cancerous one.

Scientific investigations of dreaming have been hampered by the delay between a dream and when people report on their dream, and by a change in state from sleep to wake. To overcome this problem, Konkoly et al. show that individuals in REM sleep can perceive and answer an experimenter’s questions, allowing for real-time communication about a dream.

Scientists from EPFL and IBM Research Europe have demonstrated the generation of tunable and coherent frequency combs in a pair of hybridised optical microresonators.

Although the definitive causes of Alzheimer’s diseases aren’t yet fully understood, one of the leading suspects is the accumulation of abnormal proteins in the brain that impinges on the activity of the neurons. Scientists at Northwestern University have explored this phenomenon in a group of elderly individuals with excellent memory, known as SuperAgers, and found them to be far more resistant to the troublesome buildup of some of these proteins, shedding further light on how the disease may take hold.

A lot of the research into the progression of Alzheimer’s focus on a pair of proteins called amyloid and tau. Clumps of amyloid are thought to build up and develop into plaques that impact on memory and cognitive function, while tau takes the form of tangles that interfere with the way nutrients are taken up by the neurons, eventually leading to the death of the cell.

The Northwestern University researchers carried out experiments to study the prevalence of these proteins in SuperAgers, a group of subjects over the age of 80 with the memory capacity of someone 20 to 30 years younger than them. These subjects are assessed annually as part of ongoing research at Northwestern’s Mesulam Center for Cognitive Neurology and Alzheimer’s Disease.

Muffling expression of an autism-linked gene in a key song-related area of the brain renders young zebra finches unable to learn songs from older birds.

Sheltersuit by the Sheltersuit Foundation is a life-saving wind and waterproof jacket that transforms into a sleeping bag to provide immediate shelter to the homeless who deserve “warmth, protection, and dignity.” (More info: https://youtu.be/_HOec-P6Jl4)

https://youtu.be/_HOec-P6Jl4

Pulsed lasers repeatedly emit light for a short period of time as if blinking. They have the advantage of focusing more energy than a continuous wave laser, whose intensity is kept unchanged over time. If digital signals are loaded in a pulsed laser, each pulse can encode one bit of data. In this respect, the higher the repetition rate, the more the amount of data that can be transmitted. However, conventional optical-fiber-based pulsed lasers have typically had a limitation in increasing the number of pulses per second above the MHz level.

The Korea Institute of Science and Technology (KIST) announced that the research team led by Senior Researcher Dr. Yong-Won Song at the Center for Opto-Electronic Materials and Devices was able to generate laser pulses at a rate at least 10000 times higher than the state of the art. This achievement was accomplished by inserting an additional resonator containing graphene into a fiber-optic pulsed–laser oscillator that operates in the domain of femtoseconds (10^-15 seconds). The data transmission and processing speeds are expected to increase significantly by applying this method to data communications.

The KIST research team noted that the characteristics of the wavelength and intensity of laser light that change over time are correlated (Fourier transform). If a resonator is inserted into the laser oscillator, the wavelength of the pulsed laser is periodically filtered, thereby modifying the pattern of laser intensity change. Based on this background research, Principal Researcher Song synthesized graphene, which has the characteristics of absorbing and eliminating weak light and amplifying the intensity by passing only strong light into the resonator. This allows the laser intensity change to be accurately controlled at a high rate, and thus the repetition rate of pulses could be increased to a higher level.

Scientists are developing a range of second-generation Covid vaccines aimed at expanding protection against the disease.