The Israeli inventor of a “precision medicine” for COVID-19 is “very optimistic,” after an 88-person hospital trial entered its final day without a single patient ending up on a ventilator.
Placebo study still to come, but inventor says medication ‘could be a game changer’ after around 9 out of 10 participants in Greek trial are released from hospital within 5 days.
Electric tractor developer Solectrac has announced that its e70N tractor is now available for sale. Solectrac recently delivered the 70-horsepower, diesel-equivalent tractors to three farms in Northern California as part of a grant from the Bay Area Air Quality Management District’s Funding Agriculture Replacement Measures for Emission Reductions Demonstration Program (FARMER).
Solectrac is an electric tractor developer founded in Northern California with the goal of offering farmers independence from the pollution, infrastructure, and price volatility associated with fossil fuels.
Electrek first reported on Solectrac after it donated a Compact Electric Tractor (CET) to Jack Johnson’s nonprofit organization in Oahu, Hawaii.
But 2-AG is almost immediately converted to arachidonic acid, a building block for inflammatory compounds called prostaglandins. The researchers showed that the ensuing increase in arachidonic acid levels resulted in the buildup of a particular variety of prostaglandin that causes constriction of tiny blood vessels in the brain where the seizure has induced thatprostaglandin’s production, cutting off oxygen supply to those brain areas.
Summary: The release of 2-AG, a natural endocannabinoid that is suggested to be the brain’s equivalent to THC, dampens down seizure activity but increases post-seizure oxygen deprivation in the brain.
Source: Stanford
A marijuana-like chemical in the brain, mirroring its plant-based counterpart, packs both ups and downs.
The problem with impure RNA is that it can trigger reactions, like swelling, that can be harmful, and even life-threatening. For example, impure RNA can cause inflammation in the lungs of a patient with cystic fibrosis. Conventionally manufactured RNA has to undergo a lengthy and expensive process of purification. “Rather than having to purify RNA,” says Craig Martin, the paper’s senior author and professor of chemistry at UMass, “we’ve figured out how to make clean RNA right from the start.”
Researchers at the University of Massachusetts Amherst recently unveiled their discovery of a new process for making RNA. The resulting RNA is purer, more copious and likely to be more cost-effective than any previous process could manage. This new technique removes the largest stumbling block on the path to next-generation RNA therapeutic drugs.
If DNA is the blueprint that tells the cells in our bodies what proteins to make and for what purposes, RNA is the messenger that carries DNA’s instruction to the actual protein-making machinery within each cell. Most of the time this process works flawlessly, but when it doesn’t, when the body can’t make a protein it needs, as in the case of a disease like cystic fibrosis, serious illness can result.
One method for treating such protein deficiencies is with therapeutics that replace the missing proteins. But researchers have long known that it’s more effective when the body can make the protein it needs itself. This is the goal of an emerging field of medicine—RNA therapeutics. The problem is, the current methods of producing lab-made RNA can’t deliver RNA that is pure enough, in enough quantities in a way that’s cost-effective. “We need lots of RNA,” says Elvan Cavaç, lead author of the paper that was recently published in the Journal of Biological Chemistry, MBA student at UMass Amherst, and a recent Ph.D. graduate in chemistry, also from UMass. “We’ve developed a novel process for producing pure RNA, and since the process can reuse its ingredients, yielding anywhere between three and ten times more RNA than the conventional methods, it also saves time and cost.”
UK-based architecture firm AL_A has collaborated with Canadian energy firm General Fusion to develop the world’s first magnetized target fusion facility on the UK Atomic Energy Authority (UKAEA) campus in Culham, United Kingdom. The energy firm wanted to “transform how the world is energized by replicating the process that powers the sun and stars”. AL_A’s design proposes a first-of-its-kind facility with open spaces and see-through partitions that provides innovative carbon-free energy solutions.
The Fusion Demonstration Plant (FDP) will be a highly-efficient building that captures the technological advantage of fusion to solve global energy problems. The reactor will take on a symbolic form, sitting in the middle of a circular viewing platform. In addition to state-of-the-art facilities, the building will include gathering and exhibition areas for visitors of all ages.
MRNA vaccines have to potential to end the COVID19 pandemic. How do they work? Are they safe? And how could they’ve been developed so quickly?
The main idea of mRNA vaccines is to trick our bodies to produce part of a virus. This kickstarts our immune response, without getting us sick. All that’s needed is a part of the virus’s DNA or RNA, packaged into mRNA. Cool!
(mRNA is the technology behind the vaccines from Pfizer/BioNTech, Moderna & CureVac)
💡 Follow-up video.
2D form of carbon transforms into a high-temperature superconductor if placed near a Bose-Einstein condensate, say theorists.
Graphene can be made to superconduct by placing it next to a Bose-Einstein condensate – a form of matter in which all the atoms are in the same quantum state. According to the theorists who discovered it, this new type of superconductivity stems from interactions between the electrons in graphene and quasiparticles called “bogolons” in the condensate. If demonstrated experimentally, the work could make it possible to develop new types of hybrid superconducting devices for applications in quantum sensing and quantum computing.
Conventional superconductivity occurs when phonons – quasiparticles that arise from vibrations in a material’s crystal lattice – cause electrons in the material to pair up despite their mutual electromagnetic repulsion. If the material is cooled to sufficiently low temperatures, these paired electrons (known as Cooper pairs) can travel through it without any resistance.
Bose-Einstein condensates (BECs) form when bosons, or particles with integer quantum spin, are cooled until they are all in the same quantum state. Within this special “fifth state of matter”, quasiparticles called Bogoliubov excitations can develop. Named after the Russian physicist Nikolaï Bogoliubov, who was the first to provide a theoretical description of them, these quasiparticles are usually known as bogolons. Ivan Savenko, who led the research at the Institute for Basic Science (IBS) in Korea, explains that bogolons are similar to phonons in the sense that they also serve as mediators for electron-electron attractions.
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This video explains introduction to molecular biology.
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