Lifeboat Foundation

Circa 2020

Researchers at UC Berkeley have developed a rapid test for SARS-CoV-2 that uses an enzyme to cleave viral RNA, initiating a fluorescent signal that can be detected using a smartphone camera, and which can provide a quantitative measurement of the level of viral particles in the sample. The test produce a result in as little as 30 minutes and does not require bulky or expensive laboratory equipment.

Continue reading “CRISPR Test Uses Cell Phone Camera to Detect SARS-CoV-2” »

A ball of 4000-year-old hair frozen in time tangled around a whalebone comb led to the first ever reconstruction of an ancient human genome just over a decade ago.

Stimulation of the nervous system with neurotechnology has opened up new avenues for treating human disorders, such as prosthetic arms and legs that restore the sense of touch in amputees, prosthetic fingertips that provide detailed sensory feedback with varying touch resolution, and intraneural stimulation to help the blind by giving sensations of sight.

Scientists in a European collaboration have shown that optic nerve stimulation is a promising neurotechnology to help the blind, with the constraint that current technology has the capacity of providing only simple visual signals.

Nevertheless, the scientists’ vision (no pun intended) is to design these simple visual signals to be meaningful in assisting the blind with daily living. Optic nerve stimulation also avoids invasive procedures like directly stimulating the brain’s visual cortex. But how does one go about optimizing stimulation of the optic nerve to produce consistent and meaningful visual sensations?

Continue reading “The vision: Tailored optical stimulation for the blind” »

Several different causes of aging have been discovered, but the question remains whether there are common underlying mechanisms that determine aging and lifespan. Researchers from the Max Planck Institute for Biology of Ageing and the CECAD Cluster of Excellence in Ageing research at the University Cologne have now come across folate metabolism in their search for such basic mechanisms. Its regulation underlies many known aging signaling pathways and leads to longevity. This may provide a new possibility to broadly improve human health during aging.

In recent decades, several cellular signaling pathways have been discovered that regulate the lifespan of an organism and are thus of enormous importance for aging research. When researchers altered these signaling pathways, this extended the lifespan of diverse organisms. However, the question arises whether these different signaling pathways converge on common metabolic pathways that are causal for longevity.

We probably cannot slow the rate at which we get older because of biological constraints, an unprecedented study of lifespan statistics in human and non-human primates has confirmed.

The study set out to test the ‘invariant rate of aging’ hypothesis, which says that a species has a relatively fixed rate of aging from adulthood. An international collaboration of scientists from 14 countries, including José Manuel Aburto from Oxford’s Leverhulme Centre for Demographic Science, analyzed age-specific birth and death data spanning centuries and continents. Led by Fernando Colchero, University of Southern Denmark and Susan Alberts, Duke University, North Carolina, the study was a huge endeavor requiring monitoring wild populations of primates over several decades.

Jose Manuel Aburto says, Our findings support the theory that, rather than slowing down death, more people are living much longer due to a reduction in mortality at younger ages. We compared birth and death data from humans and non-human primates and found this general pattern of mortality was the same in all of them. This suggests that biological, rather than environmental factors, ultimately control longevity.

Hugh Herr is building the next generation of bionic limbs, robotic prosthetics inspired by nature’s own designs. Herr lost both legs in a climbing accident 30 years ago; now, as the head of the MIT Media Lab’s Biomechatronics group, he shows his incredible technology with the help of ballroom dancer Adrianne Haslet-Davis, who lost her left leg in the 2013 Boston Marathon bombing.

Automated data searches and new customized patient care are the future of cancer treatment.

Each day information floods into every cancer clinic. Oncologists are scrambling for new ways to tap it to deliver the best of modern cancer care.

This article was produced by Hackensack Meridian Health in partnership with Scientific American Custom Media, a division separate from the magazine’s board of editors.

Continue reading “A New Challenge For Personalized Cancer Care: The Information Explosion” »

A supply-chain component lays open camera feeds to remote attackers thanks to a critical security vulnerability.

Millions of connected security and home cameras contain a critical software vulnerability that can allow remote attackers to tap into video feeds, according to a warning from the Cybersecurity and Infrastructure Security Agency (CISA).

The bug (CVE-2021–32934, with a CVSS v3 base score of 9.1) has been introduced via a supply-chain component from ThroughTek that’s used by several original equipment manufacturers (OEMs) of security cameras – along with makers of IoT devices like baby-and pet-monitoring cameras, and robotic and battery devices.

Man watered dish to cool it down but overheating knocked it offline for 7 hours.