Lifeboat Foundation

“Prime Editing is a wonderful example of the revolution in genetic medicine that we are living through,” said Robert Nelsen, co-founder and Managing Director of ARCH Venture Partners, one of several companies to fund Prime Medicine. “Gene editing technologies like this, when mature, could totally change our conception of what’s possible in treating disease.”

“This is an opportunity to take a giant step toward cures for a much wider range of diseases than previously possible,” said Stephen Knight, President and Managing Partner of F-Prime Capital, another backer of the new company.

The funds raised will be used to continue building the company, expand the capabilities of its technology platform and rapidly advance towards clinical indications. By the end of 2021, Prime Medicine expects to employ more than 100 people full-time.

A new way of producing coherent light in the ultra-violet spectral region, which points the way to developing brilliant table-top x-ray sources, has been produced in research led at the University of Strathclyde.

The scientists have developed a type of ultra-short wavelength coherent light source that does not require laser action to produce coherence. Common electron-beam based light sources, known as fourth-generation light sources, are based on the free-electron laser (FEL), which uses an undulator to convert electron beam energy into X-rays.

Coherent light sources are powerful tools that enable research in many areas of medicine, biology, material sciences, chemistry, and physics.

Harvard scientists have found that a single dose of psilocybin given to mice induces a rapid and long-lasting increase in connections between pyramidal neurons in the medial frontal cortex, an area of the brain known to be involved in control and decision-making. Their new findings are published in the journal Neuron.

Psilocybin — the active component in so-called “magic” mushrooms — has been shown to have profound and long-lasting effects on personality and mood. Preliminary studies have provided hope that psilocybin could help to relieve depression symptoms and treat other mental disorders. But the mechanisms behind these effects remain unclear.

A team of researchers at Yale University were interested in examining whether the lasting therapeutic effects of psilocybin might be caused in part by the substance’s ability to enhance neuroplasticity in the brain.

Unlike DeepMind, the UW Medicine team’s method, which they dubbed RoseTTAFold, is freely available. Scientists from around the world are now using it to build protein models to accelerate their own research. Since July, the program has been downloaded from GitHub by over 140 independent research teams.

Accurate protein structure prediction now accessible to all.

Scientists have waited months for access to highly accurate protein structure prediction since DeepMind presented remarkable progress in this area at the 2020 Critical Assessment of Structure Prediction, or CASP14, conference. The wait is now over.

Continue reading “Advanced New Artificial Intelligence Software Can Compute Protein Structures in 10 Minutes” »

Something to consider.

“The whole idea of lifestyle choices as something everyone can tap into is misleading, when in fact that choice is constrained by what is available to people,” he said. “This is where policy solutions or investments into these neighborhoods to make up for historical disinvestment becomes so important.”

Summary: The neighborhood you live in could have an impact on your brain and cardiovascular health, a new study reports.

Continue reading “Where You Live Can Greatly Affect Your Heart and Brain Health” »

To date, there are no effective antidotes against most virus infections. An interdisciplinary research team at the Technical University of Munich (TUM) has now developed a new approach: they engulf and neutralize viruses with nano-capsules tailored from genetic material using the DNA origami method. The strategy has already been tested against hepatitis and adeno-associated viruses in cell cultures. It may also prove successful against coronaviruses.

There are antibiotics against dangerous bacteria, but few antidotes to treat acute viral infections. Some infections can be prevented by vaccination but developing new vaccines is a long and laborious process.

Now an interdisciplinary research team from the Technical University of Munich, the Helmholtz Zentrum München, and the Brandeis University (USA) is proposing a novel strategy for the treatment of acute viral infections: The team has developed nanostructures made of DNA, the substance that makes up our genetic material, that can trap viruses and render them harmless.

The CASC announced its plans to build a reusable space transport system last year, which would involve building a series of spacecraft that take off and land like regular planes, but can reach any corner of the earth within an hour by flying at least five times the speed of sound at a suborbital altitude.

Friday’s test of an experimental vessel is a step towards the development of a hypersonic vehicle that could reach any corner of the Earth within an hour.

Hubble is back!

The Hubble Space Telescope has powered on once again! NASA was able to successfully switch to a backup computer on the observatory on Friday (July 16) following weeks of computer problems.

On June 13, Hubble shut down after a payload computer from the 1980s that handles the telescope’s science instruments suffered a glitch. Now, over a month since Hubble ran into issues, which the Hubble team thinks were caused by the spacecraft’s Power Control Unit (PCU), NASA switched to backup hardware and was able to switch the scope back on.

China is playing the long game. It plans to become the leading power in space sometime in the 2040s, through a mixture of its own perseverance and America’s decline.

The eagle and the rabbitHalf a century on, the race back to the Moon looks markedly different from the first.