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The future of vaccines may look more like eating a salad than getting a shot in the arm. UC Riverside scientists are studying whether they can turn edible plants like lettuce into mRNA vaccine factories.

One of the challenges with this new technology is that it must be kept cold to maintain stability during transport and storage. If this new project is successful, plant-based mRNA vaccines — which can be eaten — could overcome this challenge with the ability to be stored at room temperature.

The project’s goals, made possible by a $500,000 grant from the National Science Foundation, are threefold: showing that DNA containing the mRNA vaccines can be successfully delivered into the part of plant cells where it will replicate, demonstrating the plants can produce enough mRNA to rival a traditional shot, and finally, determining the right dosage.

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Watch the full documentary on Vimeo on demand: https://vimeo.com/ondemand/339083

The study of consciousness needs to be lifted out of the mysticism that has dominated it. Consciousness is not just a matter of philosophy or spirituality. It’s a matter of hard science. It’s a matter of understanding the brain and the mind — a pattern structure made out of information. It’s also a matter of engineering. If we can understand the functionality of the brain, its neural code, then we can build the same functionality into our computer systems. There’s no consensus on what produces consciousness, but everyone regardless of metaphysical views can agree what it is like to be conscious. Given that consciousness is subjectivity, what consciousness is like is what consciousness is.

‘Mind’ and ‘Consciousness’ are two different but somewhat overlapping terms related to the phenomenality of our experiential reality. Different species have a variety of their biological information processors which unsurprisingly results in qualia diversity. All species live in their own unique sensory universes. There is “something it is like to be” an organism. The human brain, our biological “wetware,” has a fractal structure on many genetic and abstract cognitive levels. Information is “modus operandi” of consciousness.

If we are to reason for the non-dual picture of the world then quantum physics is directly linked to consciousness. The human brain is a physical organ that transmits and interprets electrochemical signals. Its biochemistry is certainly governed by quantum physical laws, and consciousness — which is clearly related to the functioning of the brain — must therefore be related to the quantum physical processes going on within the brain and in the cosmos at large. Research has shown that consciousness is non-local, a scientific way of alluding to a connection within a higher dimensional order. Matter has also been shown to be non-local, which hints that matter might be an expression of consciousness, emerging from the ‘Unified Field’ — the quantum layer of pure potentiality — the code layer beneath all dimensions where time and space are information.

Continue reading “Consciousness: Evolution of the Mind, Documentary (2021), Official Teaser Trailer” | >

GM Defense, a subsidiary of General Motors, was recently awarded a contract to develop next-generation SUVs for the government’s fleet.

This specific contract was awarded by the US Department of State, and the vehicles will be built to support the Diplomatic Security Service. Diplomatic Security is a federal law enforcement agency charged with securing diplomatic assets and personnel. In 2,020 GM Defense also got the contract to build the army’s new infantry squad vehicle based on the Chevrolet Colorado ZR2. That particular contract was more extensive and, at the time of writing, valued at $213.4 million. The eventual goal was 2,065 vehicles.

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Molnupiravir, a wide-spectrum antiviral that is currently in phase 2/3 clinical trials for the treatment of COVID-19, is proposed to inhibit viral replication by a mechanism known as ‘lethal mutagenesis’. Two recently published studies reveal the biochemical and structural bases of how molnupiravir disrupts the fidelity of SARS-CoV-2 genome replication and prevents viral propagation by fostering error accumulation in a process referred to as ‘error catastrophe’.

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[Matt] from [DIY Perks] has made a name for himself building nice custom computing machines, and his latest triple-monitor luggable PC (video after the break) is sure to give most high-performance desktop machines a run for their money.

The large central monitor folding laptop monitors mounted vertically on either size look impressive, but only just scratches the surface of this build. Hidden behind aluminum panels are Ryzen 5950X CPU and RTX 3,080 GPU with water cooling, 64 GB of RAM, and two 8 TB SSDs. A set of high-quality speaker drivers, subwoofer, and audio amps is also included. All this hardware pulls about 600 W of power from a large DC-DC converter block, which in turn receives power from either a pair of onboard AC-DC converters or a 16 V – 63 V DC source, like a battery system.

To mount everything to the back of the main monitor, [Matt] created 3D printed adaptor blocks with threaded inserts which slide under existing hooks on the back of the monitor. Aluminum angles screw to these blocks to cover the edges of the display panel, together with a large mounting plate with pre-drilled holes to mount all the components on standoffs. A set of adjustable and removable legs mount to the side of the PC. A hinged door in the back cover allows storage space for a keyboard and mouse during transport. When folded, the laptop monitors don’t fully cover the main monitor, so [Matt] created a leather cover that doubles as a cable and accessory organizer.

Continue reading “Triple Monitor Luggable PC Is An All In One Powerhouse” | >

MASK Architects has designed the world’s first steel 3D printed structure of modular houses for Nivola Museum’s visitors, Tourists and Artists in Orani, city of Sardinia. Öznur Pınar Cer and Danilo Petta have Inspired from the work of “Costantino Nivola”, they have designed “Exosteel Mother Nature” modular houses which they have taken inspiration from him sculpture called the “La Madre”.

The studio is the first architecture and design studio in the world to use a steel 3D-printed “exoskeleton” construction system that supports and distributes all the functional elements of the building, using their new solution of construction technique which they called “EXOSTEEL”.

The house is composed firstly by a hollow central column inserted for one / third of its length into the ground and by various organic branches that support the three floors of the building. On each floor a perimeter frame divides and supports the facades made up of panels modeled to follow the organic shape of the house.

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Pfizer Inc (PFE.N) said on Thursday it was recalling all lots of its anti-smoking treatment, Chantix, due to high levels of cancer-causing agents called nitrosamines in the pills.

The drugmaker paused distribution of the drug in June, and has already recalled a number of lots of the medicine so far. [USN: L4N2PK3WK]

Pfizer asked wholesalers and distributors on Thursday to stop the use and distribution of the tablets immediately.

Pfizer Inc said on Thursday it was recalling all lots of its anti-smoking treatment, Chantix, due to high levels of cancer-causing agents called nitrosamines in the pills.

Continue reading “Pfizer recalls all lots of anti-smoking drug over carcinogen presence” | >

Only two new coronaviruses have spread globally the past 2 decades: SARS-CoV, which caused an outbreak of severe acute respiratory syndrome (SARS) in 2,003 and SARS-CoV-2, the virus that causes COVID-19. But that may just be the tip of the iceberg of undetected infections with related viruses emerging from bats, a new paper claims. In a preprint published yesterday researchers estimate that an average of 400,000 people are likely infected with SARS-related coronaviruses every year, in spillovers that never grow into detectable outbreaks.

The researchers, including Peter Daszak from the EcoHealth Alliance and Linfa Wang from Duke-NUS Medical School in Singapore, created a detailed map of the habitats of 23 bat species known to harbor SARS-related coronaviruses, the group to which SARS-CoV and SARS-CoV-2 belong, and then overlaid it with data on where humans live to create a map of potential infection hot spots. They found that close to 500 million people live in areas where spillovers can occur, including northern India, Nepal, Myanmar, and most of Southeast Asia. The risk is highest in southern China, Vietnam, Cambodia, and on Java and other islands in Indonesia (see map, below).

Study pinpoints Asian regions that could spark the next coronavirus pandemic.

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A new Rutgers study will examine how COVID-19 is affecting individuals in a number of cognitive-related areas, including memory loss, “brain fog,” and dementia.

“Many people who recover from mild or moderate COVID-19 notice slowed thinking or memory loss, and this motivated us to leverage our experience in studying cognitive issues related to Alzheimer’s disease, multiple sclerosis, and HIV to examine this phenomenon,” said Dr. William T. Hu, associate professor and chief of cognitive neurology at Rutgers Robert Wood Johnson Medical School and the Institute for Health, Health Care Policy, and Aging Research.

A leading cognitive neurologist and neuroscientist, Dr. Hu is spearheading the characterization of cognitive impairment following mild-to-moderate COVID-19 at Rutgers.

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In semiconductor device applications, there is an increasing demand for semiconductors with very high carrier concentrations. The semiconductor material parameters, namely carrier density and mobility, primarily determine device performance. Hence, it is important to accurately characterize the carrier density and mobility of a semiconductor for the development of its device applications.

The use of THz waves, or with wavelengths of around 300 µm and frequency of about 1 THz, in the nondestructive testing of semiconductors has been continuously expanding. Free carriers in a material absorb THz radiation, which makes it possible to estimate the electrical properties of semiconductors using THz waves.

Researchers at Osaka University, in collaboration with Nippo Precision Co., Ltd., developed a THz time-domain ellipsometry system (Tera Evaluator) that extends the range of carrier concentrations measurable by THz waves up to ~1020 cm-3 and potentially higher by improving the precision of said optical technique. In THz time-domain ellipsometry, linearly polarized THz pulses are incident on a sample and the electric field strength of the reflected THz waves as a function of time is measured. Specifically, the reflected waves polarized in the direction parallel ℗ and perpendicular (s) to the plane of incidence are of interest. The ratio of the p-and s-polarization components yields information on the electric permittivity of the sample, allowing for the evaluation of the carrier density and mobility. As such, unlike THz time-domain spectroscopy, THz time-domain ellipsometry does not require reference measurements through an aperture or standard mirror.

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