Lifeboat Foundation

Multiple human organ chips that quantitatively predict drug pharmacokinetics may offer better, accelerated drug testing.

Quantifications are produced by several disciplinary houses in a myriad of different styles. The concerns about unethical use of algorithms, unintended consequences of metrics, as well as the warning about statistical and mathematical malpractices are all part of a general malaise, symptoms of our tight addiction to quantification. What problems are shared by all these instances of quantification? After reviewing existing concerns about different domains, the present perspective article illustrates the need and the urgency for an encompassing ethics of quantification. The difficulties to discipline the existing regime of numerification are addressed; obstacles and lock-ins are identified. Finally, indications for policies for different actors are suggested.

My latest blood test results are in-how’s my biological age?

In the video I discuss my dietary approach prior to my latest blood test, the blood test results, and my plan to improve them going forward.

A breakthrough COVID-19 treatment using pineapples has been accidently discovered by Australian scientists, but how does it compare to a vaccine?

Angela Cox speaks with Professor David Morris, the man behind the discovery.

“Observations of metastasising cells revealed something intriguing—a high level of something called methylmalonic acid (MMA), a metabolic byproduct that appears to accumulate as we get older.”

“So how does MMA induce these changes in cancer cells? The key seems to be in a sort of reprogramming that “switches on” a gene called SOX4.

Prior research has shown SOX4 encourages cancer cells to become more aggressive and prone to metastasis.

Continue reading “Study finds cancer-boosting culprit that multiplies with age” »

Research is showing a strong link between handgrip strength, walking speed, and cognition, indicating how improved physical health could boost elderly minds.

Based at Barwon Health, in the heart of Geelong’s clinical health precinct, researchers are working to identify the risk factors —such as changes in muscle mass, muscle strength and physical performance—for developing sarcopenia (loss of muscle mass, strength and function with advancing age) across the lifespan.

This testing involves the Geelong Osteoporosis Study (GOS) which began in the early 1990s, gathering adult participants from the electoral roll in the Barwon Statistical Division. During recent follow-up testing, researchers also measured cognitive function through a computer-based program, in tandem with physical health evaluations.

For decades, greater than 60% of the human genome was believed to be “junk DNA” that served little or no purpose in the course of human development. Recent research by Colorado State University is challenging this notion to show that junk DNA might be important after all.

A new study, published on June 5 in Aging Cell, found that a portion of noncoding genetic material, called repetitive element transcripts, might be an important biomarker of the aging process.

Tom LaRocca, an assistant professor in the Department of Health and Exercise Science and faculty member in the Columbine Heath Systems Center for Healthy Aging at CSU, led the study to investigate a growing body of evidence that repetitive elements—transposons and other sequences that occur in multiple copies in the human genome —may become active over time as we age.

The rare satellite image shows a Chinese nuclear submarine entering into the mysterious submarine cave system at Yulin Naval Base on Hainan Island.

SpaceX just plucked another payload fairing out of the sky, and you can see video of the dramatic cosmic catch.