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A new analytical technique is able to provide hitherto unattainable insights into the extremely rapid dynamics of biomolecules. The team of developers, led by Abbas Ourmazd from the University of Wisconsin–Milwaukee and Robin Santra from DESY

Commonly abbreviated as DESY, the Deutsches Elektronen-Synchrotron (English German Electron Synchrotron) is a national research center in Germany that operates particle accelerators used to investigate the structure of matter. It is a member of the Helmholtz Association and operates at sites in Hamburg and Zeuthen.

Ohio-based startup Mantium has today announced closing $12.75 million in seed funding, as well as the launch of a cloud-based AI platform — which allows users to build with large language models.

The seed round, co-led by venture funds Drive Capital and Top Harvest, will be used to source for more talent, to add more features to Mantium’s AI platform and in driving awareness around what is achievable with large language models, especially across Africa, the firm’s CEO and co-founder Ryan Sevey told TechCrunch.

It is looking to expand its team of 33 which is currently spread across nine countries, including Ghana, Nigeria and Kenya. Having a globally distributed team, Sevey said, helps in the generation of unique insights and varying problem-solving approaches around AI.

UC Berkeley physicist Norman Yao first described five years ago how to make a time crystal—a new form of matter whose patterns repeat in time instead of space. Unlike crystals of emerald or ruby, however, those time crystals existed for only a fraction of a second.

But the time has arrived for time crystals. Since Yao’s original proposal, new insights have led to the discovery that time crystals come in many different forms, each stabilized by its own distinct mechanism.

Using new quantum computing architectures, several labs have come close to creating a many-body localized version of a time crystal, which uses disorder to keep periodically-driven quantum qubits in a continual state of subharmonic jiggling—the qubits oscillate, but only every other period of the drive.

In a study published in Nucleic Acids Research, the team of cancer researcher Francis Rodier, an Université de Montréal professor, shows for the first time that cellular senescence, which occurs when aging cells stop dividing, is caused by irreversible damage to the genome rather than simply by telomere erosion.

This discovery goes against the scientific model most widely adopted in the last 15 years, which is based on one principle: telomeres, caps located at the ends of chromosomes whose purpose is to protect genetic information, erode with each cell division. When they get too short, they tell the cell to stop dividing, thus preventing damage to its DNA. Made dormant, the cell enters senescence.

For this model to be valid, the inactivation of a single should be sufficient to activate the senescence program. Rodier’s laboratory and many others had already observed that several dysfunctional telomeres were necessary.

Signup for your FREE trial to Wondrium here: http://ow.ly/NwIS30rNQ5m — Be sure to check out Sean Carroll’s series called, “Mysteries of modern physics: Time” — I highly recommend it!

A good definition of information in physics: “information contained in a physical system = the number of yes/no questions you need to get answered to fully specify the system.”

References:
Lee Smolin’s paper: https://arxiv.org/abs/2104.09945
Prior video on entropy: https://youtu.be/T6CxT4AESCQ
Wave function collapse and time: https://youtu.be/wXJ9eQ7qTQk.

Chapters:

By Jeremy Batterson 11-09-2021

The equivalent of cheap 100-inch binoculars will soon be possible. This memo is a quick update on seven rapidly converging technologies that augur well for astronomy enthusiasts of the near future. All these technologies already exist in either fully developed or nascent form, and all are being rapidly improved due to the gigantic global cell phone market and the retinal projection market that will soon replace it. Listed here are the multiple technologies, after which they are brought together into a single system.

1) Tracking.
2) Single-photon image sensing.
3) Large effective exit pupils via large sensors.
4) Long exposure non-photographic function.
5) Flat optics (metamaterials)
6) Off-axis function of flat optics.
7) Retinal projection.

1) TRACKING: this is already being widely used in so-called “go-to” telescopes, where the instrument will find any object and track it, so Earth’s rotation does not take the object viewed out of the field of vision. The viewer doesn’t have to find the object and doesn’t have to set up the clock drive to track it. Tracking is also partly used in image stabilization software for cameras and smart phones, to prevent motion blurring of images.

2) SINGLE-PHOTON IMAGE SENSORS, whether of the single-photon avalanching diode type, or the type developed by Dr. Fossum, will allow passive imaging in nearly totally dark environments, without the use of IR or other illumination. This new type of image sensor will replace the monochromatic analogue “night-vision” devices, allowing color imaging at higher resolution than they can produce. Unlike these current devices, such sensors will not be destroyed by being exposed to normal or high lighting. Effectively, these sensors increase the effective light-gathering power of a telescope by at least an order of magnitude, allowing small telescopes to see what observatory telescopes see now.