North Korea-linked ScarCruft’s Ruby Jumper uses Zoho WorkDrive C2 and USB malware to breach air-gapped systems for surveillance.
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Trojanized Gaming Tools Spread Java-Based RAT via Browser and Chat Platforms
Threat actors are luring unsuspecting users into running trojanized gaming utilities that are distributed via browsers and chat platforms to distribute a remote access trojan (RAT).
“A malicious downloader staged a portable Java runtime and executed a malicious Java archive (JAR) file named jd-gui.jar,” the Microsoft Threat Intelligence team said in a post on X. “This downloader used PowerShell and living-off-the-land binaries (LOLBins) like cmstp.exe for stealthy execution.”
The attack chain is also designed to evade detection by deleting the initial downloader and by configuring Microsoft Defender exclusions for the RAT components.
Microsoft testing Windows 11 batch file security improvements
Microsoft is rolling out new Windows 11 Insider Preview builds that improve security and performance during batch file or CMD script execution.
As Microsoft explained today, IT administrators can now enable a more secure processing mode that prevents batch files from being modified while they run by adding the LockBatchFilesInUse registry value under HKEY_LOCAL_MACHINE\Software\Microsoft\Command Processor.
Policy authors can also enable this mode using the LockBatchFilesWhenInUse application manifest control.
NIK-driven IL-23 production by myeloid cells is a key factor in the development of autoimmune inflammation
Nishada Ramphal, Ari Waisman et al. (Johannes Gutenberg-Universität Mainz) reveal that NIK drives neuroantigen-specific T cell priming by regulating antigen presentation and IL-23 production, identifying NIK as a key orchestrator of myeloid-driven CNS autoimmunity.
Neuroinflammation.
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Teaching NeuroImage: Honeycomb Appearance of the Basal Ganglia Suggests Biallelic Nitrilase-1 Variants
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Micro- and nanoplastics facilitate the propagation of antimicrobial resistance in mixed microbial consortia
Zhen et al. show that micro-/nanoplastics increase antimicrobial resistance gene abundance and mobilization in mixed microbial consortia. Nanoplastics intensify oxidative stress and SOS responses and strengthen ARG-MGE co-localization, promoting dense horizontal gene transfer networks and turning plastisphere biofilms into resistance hotspots.
Telomere-to-telomere assembly detects genomic diversity in Canadian strains of Borrelia burgdorferi
Amin et al. present telomere-to-telomere assemblies of nine Borrelia burgdorferi strains from Canada, uncovering the diversity at chromosome ends and plasmid profiles. They identify an lp28-1a plasmid subtype and detect plasmid-chromosome recombination, offering insights into genomic plasticity and potential mechanisms of adaptation in Borrelia.
Purified diets enable experimental rigor through compositional control in animal research
Purified diets offer compositionally defined platforms that improve causal inference in nutrition studies. When aligned with the biological question, they enable targeted nutrient loss- and gain-of-function experiments, systematic lipid-source swaps, and the discovery of diet-microbiome-drug interactions. We recommend complementary validation in grain-based chow or human-relevant diets to maximize translational relevance.