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NIK-driven IL-23 production by myeloid cells is a key factor in the development of autoimmune inflammation

Nishada Ramphal, Ari Waisman et al. (Johannes Gutenberg-Universität Mainz) reveal that NIK drives neuroantigen-specific T cell priming by regulating antigen presentation and IL-23 production, identifying NIK as a key orchestrator of myeloid-driven CNS autoimmunity.

Neuroinflammation.


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