Lifeboat Foundation

Step aside, Nikon P1000, the new king of zoom is here. It’s an electronic microscope, though, but it can zoom in 100 million times and still keep the subject clear. It’s so impressive, in fact, that it earned a spot in the Guinness World Records.

Although electron microscopes allow scientists to see individual atoms, zooming all that far will not result in a sufficiently clear image. It’s due to the aberrations in the lenses which are corrected with special aberration correctors. But the problem is that you can’t stack those correctors forever.

David Muller and Sol Gruner, physics professors of Cornell University, came up with a new approach that they first introduced back in 2018. Their electron microscope achieves high resolution using a high-powered detector and a technique called ptychography. Thanks to this technique, they could capture in sharp detail even particles that measure down to 0.39 ångströms or 0.039 nanometers (one-billionth of a meter).

Is AI that learns on its own the path to truly intelligent machines?

Can there be life in exotic solvents? — such as sulfuric acid?

New results cast doubt on the presence of life in the Venusian atmosphere.

Innovating At The Frontiers Of Cancer Biology — Dr. Jonathan Chernoff MD, PhD, Senior Vice President, Deputy Director, and Chief Scientific Officer, Fox Chase Cancer Center.

Dr. Jonathan Chernoff, MD, PhD, is Senior Vice President, Deputy Director, and Chief Scientific Officer, at Fox Chase Cancer Center (https://www.foxchase.org/) where he coordinates and charts the future course of research for the organization.

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It is said that 10 to 15% of the world’s agricultural production loss is caused by diseases, which is equivalent of the food for about 500 million people. And since 70–80% of this plant disease is caused by filamentous fungi, protecting crops from filamentous fungi is an important issue in effectively feeding the world population. In order for pathogenic fungi to infect plants, they must break through the epidermal cells of the plant and invade the interior. In other words, plant epidermal cells act as the first barrier to stop the attack of pathogenic fungi in the environment. So what kind of defense functions do epidermal cells have?

Interestingly, it was known that the epidermis of plants contain small chloroplasts that are not so involved in photosynthesis. However, it was unclear what function it had. Why are there small chloroplasts in the epidermis of plants that do not contribute much to photosynthesis?

Assistant Professor Hiroki Irieda of the Faculty of Agriculture, Shinshu University and Professor Yoshitaka Takano, Graduate School of Agriculture, Kyoto University, found that small chloroplasts in the epidermis of plants control the entry of fungal pathogens. The duo discovered that the small chloroplasts move inside the cell dramatically to the surface layer in response to the fungal attack and is involved in such defense response. Furthermore, the duo found that multiple immune factors involved in the defense response of plants are specifically found in the epidermal chloroplast, which contributes to the enhancement of resistance to the invasion of pathogen filamentous fungi.

Microsoft reveals plans to bring GPT-3, best known for generating text, to programming. “The code writes itself,” CEO Satya Nadella says.

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Transmission electron microscopy (TEM) is a technique that involves beaming electrons through a specimen to form an image. This enables the generation of significantly higher resolution than traditional optical microscopes. While the latter devices are typically limited to around 1000x magnification due to the resolving power of visible light, TEM can provide zoom capabilities that are orders of magnitude greater – surpassing even a scanning electron microscope (SEM).

In recent years, TEM instruments have begun to reach extraordinary levels of detail. Spatial resolutions are now edging into the realm of individual atoms, measuring less than 0.0000005 millimetres (mm).

However, TEM is prone to lens aberrations and multiple scattering, limiting its use to samples thin enough to let electrons pass through. The process is technically challenging and requires additional tools to perform. In 2018, researchers at Cornell University offered a potential solution. They built a high-powered detector combined with a new algorithm-driven process called ptychography. This achieved a new record for microscopic resolution, tripling the previous state-of-the-art.

Scientists from Japan’s RIKEN Institute have developed a new ‘dry transfer technique’ which enables the precise positioning of optical-quality carbon nanotubes, without needing a solvent.