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One group of mice received regular doses of the Yamanaka factors from the time they were 15 months old until 22 months, approximately equivalent to age 50 through 70 in humans. Another group was treated from 12 through 22 months, approximately age 35 to 70 in humans. And a third group was treated for just one month at age 25 months, similar to age 80 in humans.

LA JOLLA—(March 7, 2022) Age may be just a number, but it’s a number that often carries unwanted side effects, from brittle bones and weaker muscles to increased risks of cardiovascular disease and cancer. Now, scientists at the Salk Institute, in collaboration with Genentech, a member of the Roche group, have shown that they can safely and effectively reverse the aging process in middle-aged and elderly mice by partially resetting their cells to more youthful states.

“We are elated that we can use this approach across the life span to slow down aging in normal animals. The technique is both safe and effective in mice,” says Juan Carlos Izpisua Belmonte, co-corresponding author and a professor in Salk’s Gene Expression Laboratory. “In addition to tackling age-related diseases, this approach may provide the biomedical community with a new tool to restore tissue and organismal health by improving cell function and resilience in different disease situations, such as neurodegenerative diseases.”

A new photo of Magic Leap 2 appears to show the device’s controller equipped with cameras for inside-out tracking which would be the first time we’ve seen the approach employed in a commercial XR headset.

Though we learned plenty of interesting details about the forthcoming Magic Leap 2 AR headset back in January, it looks like there’s still some secrets left to uncover.

A recent photo of Magic Leap 2 posted by Peter H. Diamandis is, as far as we know, the first time we’ve gotten a clear look at the front of the Magic Leap 2 controller. The photo clearly shows what appear to be two camera sensors on the controller, indicating a high likelihood it will have on-board inside-out tracking.

The superconducting magnet seen here could be the key ingredient in finally producing a commercial fusion reactor.

The magnet will be deployed in the SPARC tokamak developed by MIT which is currently under construction with a 2025 completion date.

Drugs are polluting rivers and adding to the resistance crisis as well as affecting riverine ecosystems.

Pharmaceutical pollution in the world’s rivers is threatening environmental and human health and the attainment of UN goals on water quality, with developing countries the worst affected, a global study warns.

Active pharmaceutical ingredients (APIs) could be contributing to antimicrobial resistance in microorganisms, and may have unknown long-term effects on human health, as well as harming aquatic life, according to the report published in Proceedings of the National Academy of Sciences.

Continue reading “Drugs pollute rivers, add to resistance crisis” »

Using corn for fuel seems like a dumb idea in light of new research.

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Continue reading “America Was Wrong About Ethanol — Study Shows” »

A nuclear reactor at an Illinois energy plant is helping University of Chicago scientists learn how to catch and understand the tiny, elusive particles known as neutrinos.

At Constellation’s (formerly Exelon) Dresden Generating Station in Morris, Illinois, the team took the first measurements of neutrinos coming off a nuclear reactor with a tiny detector. These particles are extremely hard to catch because they interact so rarely with matter, but power reactors are one of the few places on Earth with a high concentration of them.

“This was an exciting opportunity to benefit from the enormous neutrino production from a reactor, but also a challenge in the noisy industrial environment right next to a reactor,” said Prof. Juan Collar, a particle physicist who led the research. “This is the closest that neutrino physicists have been able to get to a commercial reactor core. We gained unique experience in operating a detector under these conditions, thanks to Constellation’s generosity in accommodating our experiment.”

Jones Food Company Ltd wants permission to change the use of the former JD Norman Foundry in Lydney to provide an indoor hydroponic farming facility gloucestershirelive.

A good article on how to understand peer review and its importance in the advancement of science.

Peer review is the lifeblood of good science. But understanding the process can take time, and gaining review experience can be daunting. Marc Gillett explains the key elements of this critical component of science.

Early career research.

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An experimental new type of cancer treatment has yielded some impressive results in mice: the eradication of advanced-stage ovarian and colorectal cancer in the animals as little as six days.

The new therapy has only been tested in mice so far, so let’s not get too excited just yet. However, the early signs are promising, and human clinical trials could be underway by the end of the year.

The treatment involves tiny ‘drug factory’ beads that are implanted into the body and deliver a continuous, high dose of interleukin-2 (IL2) – a natural compound that enlists white blood cells in the fight against cancer.