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Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S. Scientists have discovered some genetic variants that increase the risk for developing Alzheimer’s; the most well-known of these for people over the age of 65 is the APOE ε4 allele. Although the association between APOE4 and increased AD risk is well-established, the mechanisms responsible for the underlying risk in human brain cell types has been unclear until now.

Researchers from Boston University School of Medicine (BUSM) have discovered two important novel aspects of the gene: 1) human genetic background inherited with APOE4 is unique to APOE4 patients and 2) the mechanistic defects due to APOE4 are unique to human cells.

Our study demonstrated what the APOE4 gene does and which brain cells get affected the most in humans by comparing human and mouse models. These are important findings as we can find therapeutics if we understand how and where this risk gene is destroying our brain.

The need to find alternative sources for fertilizer have become urgent as chemical fertilizer shortages from the Ukrainian war threaten countries globally.


A Chinese military analyst suggested countermeasures for the Starlink satellite system developed by Musk’s SpaceX – including ways to hack or destroy the service.

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A Chinese military analyst suggested that Beijing should develop countermeasures for the Starlink satellite system developed by Elon Musk’s SpaceX — including ways to hack or even destroy the service during a time of conflict.

In a recent paper published in a China-based academic journal called Modern Defense Technology, analyst Ren Yuanzhen argued that China’s military needs to develop the capability of tracking each of the thousands of satellites set to comprise the Starlink constellations in the coming years.

Ren’s paper noted that Starlink could be a key resource for the US military, both as a means of providing internet connectivity for troops and as a source of intelligence through satellite imagery.

After a Sydney-based firm built the world’s first atomic-scale quantum integrated circuit.

Sydney-based firm Silicon Quantum Computing (SQC) built the first integrated silicon quantum computer circuit manufactured at the atomic scale, in what has been touted as a “major breakthrough” on the road to quantum supremacy, a press statement reveals.

The atomic-scale integrated circuit, which functions as an analog quantum processor, may be SQC’s biggest milestone since it announced in 2012 that it had built the world’s first single-atom transistor.