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Patients Microdose GLP-1s Without Clinician Input

About 1 in 7 users (14.6%) of injectable GLP-1 receptor agonists (RAs) have taken or are taking them at lower doses than those approved by the FDA, and many decided to do so without clinician input, a new survey found.

The most common reasons for GLP-1 RA microdosing are to manage tolerability, save money, and transition from weight loss to weight maintenance, according to the survey by Evidation, a California-based company that gathers healthcare information directly from members via its app.

The situation was far different among respondents who were actively microdosing — only 39.8% of them said they got their medication from their current healthcare clinician. Almost 24% reported getting their GLP-1 RA from a telehealth service. Less common sources included med spas, weight-loss clinics and directly from the manufacturer.

Telemedicine services typically offer lower-cost compounded versions of GLP-1 RAs, making them an attractive option for patients, noted an article in Medscape Medical News.

When asked about their most trusted source of information on microdosing, a larger percentage of GLP-1 RA users answered social media (26.8%) and online research (24.4%) than answered their healthcare clinician (20.3%).

Rare Cosmic Lineup Gives Hubble Close Look at 3I/ATLAS

NASA exoplanet probe tracks interstellar comet 3I/ATLAS to gauge its spin https://www.space.com/astronomy/comets/nasa-exoplanet-probe-…e-its-spin.

NASA’s TESS Reobserves Comet 3I/ATLAS https://science.nasa.gov/blogs/3iatlas/2026/01/27/nasas-tess…-3i-atlas/

On January 22, 2026, the NASA/ESA Hubble Space Telescope observed the interstellar comet 3I/ATLAS nearly perfectly aligned with the Sun-Earth axis, revealing unprecedented jet structures and an extended anti-tail.

A New Ingredient for Quantum Error Correction

Entanglement and so-called magic states have long been viewed as the key resources for quantum error correction. Now contextuality, a hallmark of quantum theory, joins them as a complementary resource.

Machines make mistakes, and as they scale up, so too do the opportunities for error. Quantum computers are no exception; in fact, their errors are especially frequent and difficult to control. This fragility has long been a central obstacle to building large-scale devices capable of practical, universal quantum computation. Quantum error correction attempts to circumvent this obstacle, not by eliminating sources of error but by encoding quantum information in such a way that errors can be detected and corrected as they occur [1]. In doing so, the approach enables fault-tolerant quantum computation. Over the past few decades, researchers have learned that this robustness relies on intrinsically quantum resources, most notably, entanglement [2] and, more recently, so-called magic states [3].

Novel ferroelectric ultraviolet photodetector achieves near-10,000-fold speed increase

Researchers from the Institute of Metal Research (IMR) of the Chinese Academy of Sciences have developed a new ferroelectric ultraviolet photodetector material that overcomes the long-standing performance limitations of conventional photodetectors.

This breakthrough, published in Nature Communications, promises to enable next-generation optical detection with ultra-fast speed, high sensitivity, and low noise across a wide range of applications.

Photodetectors convert light signals into electrical currents and are fundamental to modern optoelectronics. They are essential for technologies such as high-speed optical communications, environmental monitoring, and space exploration. However, creating a material that possesses all three of these qualities has been a significant challenge.

CERN chief upbeat on funding for new particle collider

Mark Thomson, the new head of Europe’s physics laboratory CERN, voiced confidence Tuesday about raising the billions of dollars needed to build by far the world’s biggest particle accelerator.

CERN, the European Organization for Nuclear Research, seeks to unravel what the universe is made of and how it works.

The planned Future Circular Collider (FCC) would be an electron-positron collider ring with a circumference of 91 kilometers and an average depth of 200 meters.

Superfluids are supposed to flow indefinitely. Physicists just watched one stop moving

Ordinary matter, when cooled, transitions from a gas into a liquid. Cool it further still, and it freezes into a solid. Quantum matter, however, can behave very differently. In the early 20th century, researchers discovered that when helium is cooled, it transitions from a seemingly ordinary gas into a so-called superfluid. Superfluids flow without losing any energy, among other quantum quirks, like an ability to climb out of containers.

What happens when you cool a superfluid down even more? The answer to this question has eluded physicists since they first started asking it half a century ago.

Beyond polymers: New state-of-the-art 3D micro and nanofabrication technique overcomes material limitations

Building things so small that they are smaller than the width of a human hair was previously achieved by using a method called two-photon polymerization, also known as 2PP—today’s state-of-the-art in 3D micro- and nanofabrication. Tiny sculptures such as a miniature replica of the Eiffel Tower or the Taj Mahal made the headlines.

Massive runaway stars in the Milky Way: Observational study explores origins and ejection process

Researchers from the Institute of Cosmos Sciences of the University of Barcelona (ICCUB) and the Institute of Space Studies of Catalonia (IEEC), in collaboration with the Institute of Astrophysics of the Canary Islands (IAC), have led the most extensive observational study to date of runaway massive stars, which includes an analysis of the rotation and binarity of these stars in our galaxy.

This study, published in the journal Astronomy & Astrophysics, sheds new light on how these stellar “runaways” are ejected into space and what their properties reveal about their fascinating origins.

Runaway stars are stars that move through space at unusually high speeds, drifting away from the places where they were born. For a long time, the way massive runaway stars acquire these high velocities has remained a mystery to astronomers, who have considered two main scenarios: a violent kick when a companion explodes as a supernova in a binary system, or a gravitational ejection during close encounters in dense, young star clusters.

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