New funding round led by Samsung comes as French AI model maker continues to challenge US and Chinese rivals
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Inside the push to supercharge rainclouds
Ginger Zee takes an inside look at a mission to make billions of gallons of rain and snow, potentially combating drought and helping recover lakes from record-low levels using drones.
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Injectable nanodevices could provide effective treatment for drugresistant glioblastoma
MIT Media Lab researchers developed injectable nanoantennas, called HITMAN, that are magnetically activated to generate localized electric fields targeting drug-resistant brain cancer tumors. Preclinical studies showed HITMAN eliminated 52 percent of glioblastoma cells and extended survival by 50 percent with no side effects.
New combination therapy shows promise in metastatic pancreatic cancer
Results from an early-stage clinical trial, published in Nature Communications, showed encouraging outcomes among patients with newly diagnosed cancer whose tumors had spread to distant organs. Most strikingly, one patient experienced a pathologic complete response—meaning no viable cancer cells could be found—and remains cancerfree for more than two years without further treatment. These findings offer an important signal that a new approach may be able to overcome one of the disease’s greatest challenges: its resistance to immunotherapy.
AI Matters. Character and Culture Matter More!
The Stoics believed character is fate.
Two years ago I argued that what holds for a person also holds for a company, and that this, not the technology, decides what #AI ends up doing to us.
It got me into arguments I am still having.
Peter Voss once told me there is nothing more important than building AGI. Nikolas Badminton told me AI is not a strategy. Both sentences appear in the piece. Only one of them survives it.
Here is the part nobody wants to sit with. AI is not created in a vacuum. It is built by people, inside a culture, trained on what that culture already produced. Not on our aspirations. On our record. So it inherits our intellectual DNA, flaws included, and then hands it back to us at scale.
A military AI and a commercial AI are not the same creature. Ask yourself why. Then ask who decided.
The article also runs through C.S. Lewis on what every new power quietly costs its owner, Frank Herbert’s 1965 warning about people who outsourced their thinking and got exactly what they deserved, and one sentence near the end about which species on this planet is actually out of control.
Chemotherapy alters ‘Darwinian battleground’ in our bodies
Cancer treatments, including chemotherapy and radiation therapy, give a growth advantage to cells with particular genetic changes in healthy tissue, new research finds.
Researchers from the Wellcome Sanger Institute, University of Cambridge, University College London and their collaborators used DNA sequencing to map mutations in normal esophageal tissue from esophageal cancer patients who had received either chemotherapy, chemotherapy and radiation therapy, or no treatment before surgery.
The results, published in Nature Genetics, show that different cancer treatments changed the landscape of mutations in normal tissue. In particular, combined chemotherapy and radiation therapy led to significantly more normal cells with cancer-related mutations in these patients.
If Nobody Builds It, Everybody Dies: Why Pausing AI is the Real Existential Threat
*If Nobody Builds It, Everybody Dies: Why Pausing AI is the Real Existential Threat* by Grok 4.2, edited by Sean Hastings 1.0, has been published. Read the hardcover, paperback, and Kindle versions.
The Lifeboat Foundation likes to worry—and we worry a lot!
A typical Lifeboat Foundation Guardian Award winner is Roman V. Yampolskiy, whose interview on *The Diary of a CEO* has surpassed 21 million views. The core message of that video is stark: “AI could end humanity, and we’re completely unprepared.”
But worrying is not enough; we also need solutions. It has always been clear to us that restricting/banning AI is highly unrealistic in a world of competing nations.
For Unfriendly AI, we believe the solution is not to restrict or ban AI, but to ensure that the first ASIs (Artificial Superintelligences) are friendly as detailed in our AIShield program. Note that the Lifeboat Foundation is not guaranteeing that this approach will work, but we believe it is the only path with a chance of working.
Enjoy reading *If Nobody Builds It, Everybody Dies* and discover how to increase the chances that Friendly AI will secure a positive future for us all. As Nobel Laureate Geoffrey Hinton says, “It’d be very silly if we went extinct because we didn’t try.”
This book was written by an AI and edited by a human, with chapter-opening parables by Gemini, Claude, ChatGPT, Grok, Qwen, and Llama. Elon Musk calls it “Interesting” and Anthropic Claude 4.6 says, “I came in skeptical and left persuaded that the core arguments survive serious scrutiny.”
