Toggle light / dark theme

Russian missiles hit Poland.


The timing of this fresh wave of Russian attacks is not lost on anybody, coming hours after President Zelenskyy addressed world leaders meeting in Bali for the G20.

(Subscribe: https://bit.ly/C4_News_Subscribe)

Watch more of our explainer series here — https://www.youtube.com/playlist?list=PLXjqQf1xYLQ6bu-iixvoFTVsiXQVlVniX
Get more news at our site — https://www.channel4.com/news/

Follow us:

Advancing Novel Therapeutic Interventions For Unmet Medical Needs — Dr. Michael Hufford, Ph.D., Co-Founder and CEO, LyGenesis; Interim CEO, Morphoceuticals; Scientific Advisor, Juvenescence.


Dr. Michael Hufford, Ph.D. is the Co-Founder and the Chief Executive Officer of LyGenesis (https://www.lygenesis.com/), a clinical-stage cell therapy company that transforms patient’s lymph nodes into bioreactors capable of growing functioning ectopic organs. He also serves as the Interim CEO of Morphoceuticals (https://www.morphoceuticals.com/) a company focused on modifying electric potentials in cells and tissues for a variety of applications in regenerative medicine, from improving amputation stump health and limb regeneration, to organogenesis, to creating a bioelectric atlas where numerous disease indications may be corrected.

Dr. Hufford also serves as a scientific advisor to Juvenescence (https://juvlabs.com/) a biotech holding company that develops therapies and products to modify aging and help people live longer.

An entrepreneur and drug developer, Dr. Hufford has over 20 years of experience in the development and FDA regulatory approval of small molecules (Cypress Bioscience), biologics (Amylin Pharmaceuticals), as well as drug delivery technologies (e-Nicotine Technology). He has designed and executed clinical trials and drug development programs across a wide variety of therapeutic areas, from orphan metabolic diseases to psychiatric and oncology indications. His experience in-and out-licensing pre-clinical and clinical stage assets, executing corporate partnering deals, and in investor relations, has helped him to raise public, private, and angel-back financing for his companies. His philanthropic work includes co-founding and serving as the CEO of Harm Reduction Therapeutics, Inc. (https://www.harmreductiontherapeutics.org/), a nonprofit pharmaceutical company developing low-cost over-the-counter intra-nasal naloxone in the US to help prevent opioid overdose deaths.

Dr. Hufford earned his undergraduate degree with distinction from Purdue University, and his master’s and doctoral degrees in Clinical Psychology from the University of Pittsburgh, before completing a Research and Clinical Fellowship in the Department of Psychiatry at Harvard Medical School. He is an award-winning lecturer, and the author of more than 100 scientific publications, presentations, and OpEds, with multiple issued and pending patents.

The patients had some, although severely diminished, visual function during the day, however, at night they were essentially blind, with light sensitivity 10,000–100,000 times less than normal.

According to researchers at the Scheie Eye Institute at the Perelman School of Medicine at the University of Pennsylvania, adults with a genetic form of childhood-onset blindness experienced remarkable recoveries of night vision within days of receiving an experimental gene therapy.

The patients had Leber Congenital Amaurosis (LCA), a congenital blindness caused by GUCY2D gene mutations. The findings were published in the journal iScience. The researchers administered AAV gene therapy, which contains the DNA.

A team of researchers at the National Ignition Facility (NIF) at the Lawrence Livermore National Laboratory, in California, has found evidence of ions behaving differently than expected in their fusion reactions.

In their paper published in the journal Nature Physics, the group describes their study of ions in the plasma generated in their . Stefano Atzeni, with Università di Roma “La Sapienza,” has published a News & Views piece in the same journal issue giving an overview of the work being done at the NIF and the effort now being conducted by the team to better understand the unexpected ion behavior.

Scientists around the world have been trying for many years to replicate the that occur in the sun—this could provide humanity a nearly limitless source of energy. Such work has been step-by-step, with researchers tweaking reactors in search of the right combination of factors to produce more energy than is used to run the reactor.

A team of scientists from the Department of Energy’s Ames National Laboratory has developed a new characterization tool that allowed them to gain unique insight into a possible alternative material for solar cells. Under the leadership of Jigang Wang, senior scientist from Ames Lab, the team developed a microscope that uses terahertz waves to collect data on material samples. The team then used their microscope to explore methylammonium lead iodide (MAPbI3) perovskite, a material that could potentially replace silicon in solar cells.

Richard Kim, a scientist from Ames Lab, explained the two features that make the new scanning probe microscope unique. First, the microscope uses the terahertz range of electromagnetic frequencies to collect data on materials. This range is far below the , falling between the infrared and microwave frequencies. Secondly, the terahertz light is shined through a sharp metallic tip that enhances the microscope’s capabilities toward nanometer length scales.

“Normally if you have a light wave, you cannot see things smaller than the wavelength of the light you’re using. And for this terahertz light, the wavelength is about a millimeter, so it’s quite large,” explained Kim. “But here we used this sharp metallic tip with an apex that is sharpened to a 20-nanometer radius curvature, and this acts as our antenna to see things smaller than the that we were using.”

Chip startup Cerebras Systems Inc. today debuted Andromeda, a supercomputer optimized to run artificial intelligence applications that features more than 13.5 million processor cores.

Sunnyvale, California-based Cerebras Systems is backed by more than $720 million in venture funding. The startup sells a chip called the WSE-2 that is specifically designed to run AI software. The new Andromeda supercomputer that Cerebras Systems debuted today is based on the WSE-2 chip.

According to Cerebras Systems, Andromeda can provide performance in excess of one exaflop when running AI applications. One exaflop equals 1 million trillion calculations per second. The startup says that Andromeda’s performance makes it suitable for, among other use cases, training large language models, which are complex neural networks that can perform tasks such as translating text and generating software code.