Summary: Dampening retromer activity slows down the trafficking of tau in neurodegenerative disorders, a new study reports.
Source: EPFL
Neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease are associated with atypical proteins that form tangles in the brain, killing neurons. Neurobiologists at EPFL have now identified some key mechanisms underlying the formation of these tangles.
Worried about the Chinese threat to Taiwan, the U.S. and others have tried to expand their piece of the island’s semiconductor production.
This week our guest is author and technologist, David Weinberger, who has spent years lecturing at Harvard as well as acting as a fellow and senior researcher at the renowned Berkman Klein Center for Internet & Society. And just prior to covid, David released his latest book, Everyday Chaos: Technology, Complexity, and How We’re Thriving in a New World of Possibility. In this episode, David and I explore some of the key ideas he focused on in Everyday Chaos. This includes looking at the ways in which we have historically used reductionist thinking to make generalizations for society, products, and technology, and how the latest technologies like the internet and Machine learning are revealing how much more we can thrive when we embrace chaos and customization. This means letting individuals and data tell us what people want by exploring all the possibilities rather than attempting to predict and shape outcomes beforehand.
** Find out more about David at his website weinberger.org and buy his book at everydaychaosbook.com.
55 MINS
Russia’s national space agency Roskosmos presented a model of the planned space station, dubbed “ROSS” by Russian state media, on Monday at “Army-2022”, a military-industrial exhibition outside Moscow.
Yuri Borisov, whom President Vladimir Putin appointed last month to head Roskosmos, has said Russia will quit the ISS after 2024 and is working to develop its own orbital station.
Launched in 1998, the ISS has been continuously occupied since November 2000 under a U.S.-Russian-led partnership that also includes Canada, Japan and 11 European countries.
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A new startup named Yoodli built a free website that will analyze your speech and help you improve.
Dr. Max More is a philosopher, writer, speaker and expert in Cryonics — the process of cryopreserving a body at the time of legal death in the hopes of reviving them in the future.
Theo talks with Dr. More about what actually happens when we die, the future of mankind, and if Theo would preserve his brain for science.
Dr. More is the Ambassador for Alcor Life Extension, a non-profit in Scottsdale, Arizona practicing cryonics. Max received a Doctorate in Philosophy in 1995 from the University of Southern California after completing a degree in Philosophy, Politics, and Economics from Oxford University.
Dr. Max More: https://www.maxmore.com/
The annual Aurigid Meteor Shower peaks this Thursday, September 1. Though the Aurigids are less flashy than some (the American Meteor Society calls them a “reliable minor shower”), they still put on a show worth watching. That’s especially true since this year’s shower coincides with a waxing crescent moon, meaning moonlight won’t upstage the meteors. Here’s everything you need to know to catch the Aurigids in action.
When to see the Aurigid Meteor Shower
The Aurigids pelt our atmosphere with bits of burning rock and dust about this time every year. This year’s Aurigid shower started on August 28 and will continue until September 4 or 5, but the real show happens at the meteor shower’s peak, on September 1.
He Great Drought and Deluge is upon much of the world. These are no longer once-in-a-thousand-year events.
In one video, she runs through a field of lavender and spins around in a lilac dress. It was the beloved family dog, a chubby pug named Ben, who showed her how to twirl in circles.
“Is it possible to fall in love again and again?” her mother wrote under a photo just weeks before Liza was killed. — Jennifer Hassan
Read more: A 4-year-old killed in her stroller shows horrific toll of Russia’s war.
