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Feb 23, 2022

New project creates digital clones of human brains to help treat neurological disorders

Posted by in categories: biotech/medical, computing, mathematics, neuroscience

More recently, digital twins have been the focus of a European Union-funded project that seeks to clone a patient’s entire brain. Dubbed Neurotwin, the research project aims to create virtual models that can be used to predict the effects of stimulation for the treatment of neurological disorders—including epilepsy and Alzheimer’s disease. When it comes to epilepsy, non-invasive stimulations (where electrical currents are painlessly delivered to the brain) have proven effective in tackling seizures. Given how drugs don’t help a third of epilepsy patients, the technology is coveted yet needs refinement. This is where virtual clones come in.

“The digital avatar is essentially a mathematical model running on a computer,” Giulio Ruffini, coordinator of the Neurotwin project, told WIRED. Including a network of embedded “neural mass models,” the technology hopes to create a map of the neural connections in the brain—a concept termed as the ‘connectome’. “In the case of epilepsy, some areas of the connectome could become overexcited,” the outlet mentioned. “In the case of, say, stroke, the connectome might be altered.” Once the digital clone has been created by the team, with about half an hour-worth of magnetic resonance imaging (MRI) data and ten minutes of electroencephalography (EEG) readings to capture electrical activities and realistically simulate the brain’s main tissues (including the scalp, skull, cerebrospinal fluid, and grey and white matter), it can then be used to optimise stimulation of the real patient’s brain.

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Feb 23, 2022

Biotracking, Age Reversal & Other Advanced Health Technologies | Lifespan with Dr. David Sinclair #8

Posted by in categories: biological, life extension, wearables

No he does not respond to the resveratrol challenges. Important here are the chapters concerning Resetting the Ageing Clock and Repeatable Ageing Reversal.


In the final episode of this season, Dr. David Sinclair and Matthew LaPlante focus on current and near-future technologies relevant to health and aging. In addition to discussing the utility of wearable sensors and biological age measurements, they highlight innovative research aimed at reversing biological age. The societal effects of therapies that successfully extend healthspan and/or lifespan are also considered.

Continue reading “Biotracking, Age Reversal & Other Advanced Health Technologies | Lifespan with Dr. David Sinclair #8” »

Feb 23, 2022

Quantum gravity sensors could finally overcome a major issue raised by Einstein

Posted by in categories: electronics, quantum physics

Cartography could be changing forever as an advanced tool moves from the lab to the real world. A new quantum gravity sensor helps overcome an issue raised by Einstein.

Feb 23, 2022

Reflections on the ethics of genetic enhancement

Posted by in categories: biotech/medical, education, ethics, genetics, policy

Public policy includes efforts by governmental as well as nongovernmental agencies (other than professional associations) to manage genetic enhancement. For example, the International Olympic Committee has a policy on performance-enhancing drugs in sport. In the United States, the Food and Drug Administration classified synthetic anabolic steroids as a restricted class of drugs, making it more difficult to get access to them. Such measures will not always be successful. Epoetin alfa (EPO) is a useful medication for the many people who suffer from chronic anemia, including people who must undergo regular renal dialysis. As a consequence, it is in very wide supply for legitimate therapeutic purposes, unlike the synthetic anabolic steroids. Imposing strict limitations on access to EPO would create an enormous inconvenience for the large number of people who benefit from the drug. The fact that some athletes are able to get their hands on EPO is an unintended consequence of having the drug widely available for legitimate therapeutic uses. The appropriate public policy will not be the same, necessarily, for every drug.

By “personal policy” we mean the moral understandings and social practices of individuals, parents, and families, including those moral convictions that would cause them to refrain from unwise or unfair use of genetic enhancement technologies. The Worth of a Child, for example, focuses on ethical issues involving children and parents.11 How does one engage that sort of personal policy response? The means we have are limited but powerful: education, public dialogue, and the encouragement of ethical reflection.

In conclusion, there are four points worth reiterating. First, as we think about genetic enhancement, we should use a broad definition of genetic-enhancement technologies, not merely gene manipulation, but indirect genetic technologies, such as biosynthetic drugs. Second, we should try to anticipate the enhancement temptations of new therapies. Such anticipation may help us in shaping the marketing, availability, or other aspects of those technologies. Third, we should promote the adoption of appropriate public and professional policies. Finally, we should provide public education and dialogue to encourage personal ethical reflection on the appropriate uses and limits of genetic-enhancement technologies.

Feb 23, 2022

Look: Stunning new image of Rosette Nebula taken from backyard

Posted by in category: space

This cosmic cloud of gas and dust is about 5,000 light-years away.


“I had vowed never to sell that guitar,” Gill tells Inverse. “But I spent some more time [on astrophotography] in the last few years so I think I’ve gotten a bit more into it, and spent some more money on it.”

Gill’s latest image features a cosmic landscape of newborn stars, gas, and dust.

Continue reading “Look: Stunning new image of Rosette Nebula taken from backyard” »

Feb 23, 2022

What Is the Ocean Battery? It Could Be Crucial for Renewable Energy Storage

Posted by in categories: climatology, sustainability

“Ocean Battery resolves a societal challenge to provide access to renewable power generation without destabilizing the power grid and meet our climate goals. The Dutch Water engineers resolved this problem in a brilliant yet simple way with a tremendous amount of creativity, innovation power and Dutch entrepreneurship,” the press release continues.

Keep reading for more on this exciting new piece of technology, that could be revolutionary for the transition to cleaner means of energy.

Feb 23, 2022

Coin Cell Eliminator Does More Than Save Batteries

Posted by in categories: electronics, energy

Coin cells are useful things that allow us to run small electronic devices off a tiny power source. However, they don’t have a lot of capacity, and they can run out pretty quickly if you’re hitting them hard when developing a project. Thankfully, [bobricius] has just the tool to help.

The device is simple – it’s a PCB sized just so to fit into a slot for a CR2016 or CR2032 coin cell. The standard board fits a CR2016 slot thanks to the thickness of the PCB, and a shim PCB can be used to allow the device to be used in a CR2032-sized slot instead.

It’s powered via a Micro USB connector, and has a small regulator on board to step down the 5 V supply to the requisite 3 V expected from a typical coin cell. [bobricius] also gave the device a neat additional feature – a pair of pads for easy attachment of multimeter current probes. Simply open the jumper on the board, hook up a pair of leads, and it’s easy to measure the current being drawn from the ersatz coin cell.

Feb 23, 2022

A.I. has mastered ‘Gran Turismo’ — and one autonomous car designer is taking note

Posted by in categories: robotics/AI, transportation

A new artificial intelligence program has beaten the world’s best players in the popular PlayStation racing game Gran Turismo Sport. But the impact could be felt far beyond that.

Feb 23, 2022

What Are the Critical and Emerging Technologies to Watch as Perceived by the White House?

Posted by in category: policy

America’s Office of Science and Technology Policy, the National Science and Technology Council, and the National Security Council prioritize.

Feb 23, 2022

The world’s tiniest battery could power a new generation of wearable sensors

Posted by in categories: particle physics, robotics/AI, wearables

And it’s the size of a grain of dust. Energy storage might have been revolutionized thanks to a common dessert dish.


Advances in microelectronics have enabled the use of miniaturized computers for autonomous intelligence at the size of a dust particle less than one square millimeter across and a few hundred micrometers thick, creating an environment for ubiquitous computing. However, the size mismatch between microbatteries and microelectronics has emerged as a fundamental barrier against the take-off of tiny intelligent systems requiring power anytime anywhere. Mainstream microbattery structures include stacked thin films on the chip or electrode pillars and on-chip interdigitated microelectrodes. Nevertheless, available technologies cannot shrink the footprint area of batteries while maintaining adequate energy storage. Alternatively, the on-chip self-assembly process known as micro-origami is capable of winding stacked thin films into Swiss-roll structures to reduce the footprint area, which exactly mimics the manufacture of the most successful full-sized batteries—cylinder batteries. In addition to discussing in detail the technical difficulties of reducing the size of on-chip microbatteries with various structures and potential solutions, this Perspective highlights the following two basic requirements for eventual integration in microcomputers: minimum energy density of 100 microwatt-hour per square centimeter and monolithic integration with other functional electric circuits on the chip.