Cryo-electron microscopy structures of skeletal F-actin show solvent-driven rearrangements governing actin filament assembly and aging with potential application in design of drugs and small molecules for imaging and therapy.
On Homelessness
Posted in transhumanism
The overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer’s disease (AD), according to a new study by scientists at the University of Colorado Anschutz Medical Campus.
The gene, Kinesin-5 or KIF11, does this despite the presence of amyloid beta (Abeta), the main component of plaques in the brains of those with AD. Scientists have traditionally targeted the plaques when looking for treatments for the fatal disease. In this case, they went around them.
The study was published online last week in the journal iScience.
Go to https://nordvpn.com/isaacarthur to get a 2-year plan plus 4 additional months with a HUGE discount. It’s risk-free with Nord’s 30-day money-back guarantee!
Spaceships getting damaged or crashing is common story in science fiction but it’s also terrifyingly common with real spaceships. So what do we if our spaceship gets damaged?
Visit our Website: http://www.isaacarthur.net.
Support us on Patreon: https://www.patreon.com/IsaacArthur.
Support us on Subscribestar: https://www.subscribestar.com/isaac-arthur.
Facebook Group: https://www.facebook.com/groups/1583992725237264/
Reddit: https://www.reddit.com/r/IsaacArthur/
Twitter: https://twitter.com/Isaac_A_Arthur on Twitter and RT our future content.
SFIA Discord Server: https://discord.gg/53GAShE
Listen or Download the audio of this episode from Soundcloud: Episode’s Audio-only version: https://soundcloud.com/isaac-arthur-148927746/damaged-spacec…ed-saucers.
Episode’s Narration-only version: https://soundcloud.com/isaac-arthur-148927746/damaged-spacec…ation-only.
Credits:
If you thought it was easy to analyze brain cells, think again.
When you take a brain tissue sample, all that your analysis would normally show you is an average for all the cell types present. And since there are a whole lot of cell types in our brain— neurons and others—you’ll get a sort of cell smoothie, which makes it difficult if not impossible to tell the cells apart, let alone study them.
It is like wanting to know how many green M&M’s there are in a bowl, but instead just getting told how many colors there are. You are not really getting the answer you wanted.
The discovery of a hot spot for horizontal gene transfer draws attention to the possible roles of parasites and ecology in such changes.
After years of development, researchers have managed to shrink two-photon microscopy into a device that can be mounted on rodents’ heads without impeding behaviour.
I guess it’s time for Twitter execs to go home, and for me to start using Twitter again. They killed my chamber of commerce account, then when I opened a personal account, they kept asking for my phone number every time I logged in. If I give you my number once and you send me an sms, I’m not giving it to you again, as that’s not safe.
It ends months of bad blood between the two parties regarding the takeover, with Elon Musk complaining about fake accounts on the platform and claims by a whistleblower that Twitter misled regulators about security risks.
Meanwhile, in Kenya, Facebook to start sharing advertising data with Kenya’a tax agency, and the police.
In the terms, the company said businesses placing adverts across its different platforms would have given it consent to share information with government agencies looking for such information to assist in lawful investigations.
“Our licence to deliver your ad will end when we have completed your order. You understand, however, that…you consent that Meta may disclose your advertising content, and all information associated with your advertising, to a governmental entity or body if Meta believes that disclosure would assist in a lawful investigation,” says the company in the terms that will be effective January 3, 2023.
It added that companies placing adverts would be required to disclose information such as the nature of the business they are involved in and the kind of people targeted by such adverts.