Researchers at Karolinska Institutet, Columbia University and the University of San Francisco, have uncovered a previously unknown mechanism by which dopamine, a key brain chemical vital for movement and motivation, can affect brain activity indirectly by boosting serotonin. The study was published in Science Advances.
Dopamine is a key chemical messenger that supports many essential brain functions, including motivation, movement, and learning. Although dopamine acts throughout the brain, it plays an especially central role in the basal ganglia, a network of interconnected regions responsible for selecting which behaviors we express.
The basal ganglia and dopamine are deeply involved in neuropsychiatric and neurodegenerative diseases, and many widely used medications target this network.









