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What’s your favorite number? There are literally infinite options, and yet only a few which seem to stand out as more popular than others: there’s seven, obviously; 13 or 666 for the badasses among us; and √2 for anyone who just likes annoying Pythagoreans.

But there’s really only one number out there that can claim to be World Champion: pi. What other mathematical constant is literally used as a benchmark for computing power, or forms the basis for a never-ending worldwide grudge match over who can list the most random digits in the correct order (current record: 111,700)?

The reason pi is able to capture our imagination like this is because it is an irrational number – in other words, its decimal expansion is never-ending and entirely random. It’s thought that any sequence of numbers you can possibly think of can be found somewhere in the expansion of pi, and yet knowing any particular sequence somewhere in the expansion tells you no information about which digit comes next.

When Elon Musk posed the question to his Twitter followers as to whether or not he should resign as CEO, the majority of voters chose the latter option.

As a consequence of the poll’s findings, a number of potential candidates have been proposed to succeed Musk as Twitter’s CEO, but if popularity were a deciding factor, MrBeast would emerge as the clear victor.

His tweet proposing himself for the position has almost a million likes as of this writing, and he has ambitious aspirations for where he would lead the social networking site.

New York, NY (December 12, 2022) A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

The therapy, known as a bispecific antibody, binds to both T cells and multiple myeloma cells and directs the T cells—white blood cells that can be enlisted to fight off diseases—to kill multiple myeloma cells. The researchers described this strategy as “bringing your army right to the enemy.”

The success of the off-the-shelf immunotherapy, called talquetamab, was even seen in patients whose cancer was resistant to all approved multiple myeloma therapies. It uses a different target than other approved therapies: a receptor expressed on the surface of cancer cells known as GPRC5D.

Summary: A new brain mapping study reveals a neural network in cuttlefish that involves chemosensory function and body pattern control which the cuttlefish utilize for foraging and camouflage.

Source: University of Queensland

New mapping of the cuttlefish brain could explain how, and why, the marine animal employs its distinct camouflage ability according to researchers from The University of Queensland (UQ).

Source: Penn State

Understanding the neural interface within the brain is critical to understanding aging, learning, disease progression and more. Existing methods for studying neurons in animal brains to better understand human brains, however, all carry limitations, from being too invasive to not detecting enough information.

A newly developed, pop-up electrode device could gather more in-depth information about individual neurons and their interactions with each other while limiting the potential for brain tissue damage.