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There are many processes and proteins that help the body fight a flu infection. One of them is known as IFITM3. Researchers have now shown that this protein can help prevent viruses from mutating after they have infected a new host. But some people are deficient in IFITM3, which can raise their risk of a severe flu infection. That deficiency is not unusual in some groups. For example, around twenty percent of Chinese people and four percent of people with European ancestry carry variants in IFITM3 that can interfere with the protein’s expression. This study has shown that these genetic variants can allow flu viruses to establish infections even when the virus is present at very low levels that would not usually cause infection. The findings have been reported in Nature Communications.

The IFITM3 (interferon-induced transmembrane protein 3) protein is part of the innate immune system, and is generated at high levels after the detection of a flu infection. It can sequester viral particles so that they are not able to replicate, which reduces the severity of flu infections. Mouse models that are IFITM3 deficient are extremely vulnerable to the flu.

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As our collective nervousness over AI grows each day, “The Wild Robot” emerges from the woods with a completely different take on a man-made being with the ability to learn.

“I love the messaging of the story, the idea that kindness is a survival tactic,” says star Lupita Nyong’o. “It’s just so pure and sweet and needed.”

In the DreamWorks animated feature, a domestic helper robot, a ROZZUM 7,134 (Nyong’o), is lost on a wooded island and activated without human guidance. As the ingeniously designed “Roz” searches for a mission in a vernal bower that looks designed by an Impressionist painter, she learns to communicate with the animal residents and finds purpose in raising an orphaned gosling, Brightbill.

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During ritual ceremonies, the ancient Aztec civilization used a “death whistle” — a haunting instrument shaped like a human skull.

Its eerie, high-pitched scream is not just a product of its unique design, but a deliberate attempt to manipulate the human mind.

The Aztecs may have intentionally used this effect to enhance the terror of their sacrificial rituals.

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Summary: AI models trained on MRI data can now distinguish brain tumors from healthy tissue with high accuracy, nearing human performance. Using convolutional neural networks and transfer learning from tasks like camouflage detection, researchers improved the models’ ability to recognize tumors.

This study emphasizes explainability, enabling AI to highlight the areas it identifies as cancerous, fostering trust among radiologists and patients. While slightly less accurate than human detection, this method demonstrates promise for AI as a transparent tool in clinical radiology.

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A big day of output for the Human Cell Atlas, a global collaborative project with 100 countries to understand our ~37 trillion cells A Wikipedia of our cells, a “remarkable achievement” https://nature.com/articles/d41586-024-03754-y

In a collection of research articles and related content, the Human Cell Atlas consortium presents tools, data and ideas towards the generation of their first draft atlas of cells in the human body.

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Continue reading “Sunlight Deficiency As A Contributor To Poor Health: Roger Seheult, M.D. (‪@Medcram‬)” | >

Blue Origin today announced a multi-launch agreement to deliver multiple next-generation Block 2 BlueBird satellites to low Earth orbit (LEO) on New Glenn. All launches will occur over a multi-year period from Blue Origin’s Launch Complex 36 at Cape Canaveral Space Force Station.

AST SpaceMobile is building the first and only space-based cellular broadband network designed for both commercial and government applications. It will operate directly with everyday smartphones and allow seamless switching between terrestrial cell towers and satellite signals depending on location and coverage needs.

“New Glenn’s performance and unprecedented capacity within its seven-meter fairing enables us to deploy more of our Block 2 BlueBird satellites in orbit, helping provide continuous cellular broadband service coverage across some of the most in-demand cellular markets globally,” said Abel Avellan, Founder, Chairman, and CEO, AST SpaceMobile.

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New research into dark matter suggests it might have originated from a “Dark Big Bang,” distinct from the traditional Big Bang.

This theory, which posits a separate cosmic event as the source of dark matter, could change how we understand the universe’s early moments. Upcoming gravitational wave detection experiments could provide critical evidence to support this theory.

Alternative theory of dark matter genesis.

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