Lifeboat Foundation

All eyes are on the Emerald Isle this week as the Longevity Summit Dublin brings together a host of speakers covering the spectrum of this booming sector. Delegates have been hearing from some of the leading entrepreneurs, companies, investors, and researchers in the field as they address many of the hot-button topics affecting longevity. One of those speakers is the so-called “father of genomics” – Harvard professor of genetics, George Church – who closes the conference later today with a keynote on Gene, cell and organ therapies for de-aging.

Longevity. Technology: In addition to his Harvard professorship, Church heads up synthetic biology at the Wyss Institute, where he oversees development of new tools with applications in regenerative medicine. Much of his focus more recently has been on the development of gene therapies targeting age-related disease, a passion that led him to co-found Rejuvenate Bio, with the goal of creating “full age reversal gene therapies.” We caught up with Church ahead of his Dublin presentation for a brief conversation on longevity.

Dr Church’s name is synonymous with genomic science, and he was a key contributor to the Human Genome Project and technologies including next-generation fluorescent and nanopore sequencing, aimed at understanding genetic contributions to human disease. However, he doesn’t feel that those initiatives did a huge amount to move the aging field forward.

https://www.youtube.com/watch?v=NsWOZ4IAHNU

If there is one thing science fiction movies and comics have taught us, it’s that humans have no.
limitations, and we will one day be able to open a portal that transverses into another dimension. What if I tell you that day is closer to us than ever? This is the latest discovery made.
by scientists and is by far the biggest of the century.
Will we finally get to find out if we are the only beings in the cosmos? What technology have.
scientists designed capable of making interstellar teleportation possible? How and where will.
the portals take us?
Join us as we explore how scientists have finally found a way to open a portal to another.
dimension.

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Scientist from the National University of Singapore (NUS) have found a novel way of growing cell-based meat by zapping animal cells with a magnet. This new technique simplifies the production process of cell-based meat by reducing reliance on animal products, and it is also greener, cleaner, safer and more cost-effective.

Cultured meat is an alternative to animal farming with advantages such as reducing carbon footprint and the risk of transmitting diseases in animals. However, the current method of producing cultured meat involves using other animal products, which largely defeats the purpose, or drugs to stimulate the growth of the meat.

To cultivate cell-based meat, animal cells are fed animal serum—usually fetal bovine serum (FBS), which is a mixture harvested from the blood of fetuses excised from pregnant cows slaughtered in the dairy or meat industries—to help them grow and proliferate. This is a critical, yet cruel and expensive, step in the current cell-based meat production process. Ironically, many of these molecules come from the muscles within the slaughtered animal, but scientists did not know how to stimulate their release in production scale bioreactors. Other methods to promote cell growth are using drugs or relying on genetic engineering.

Researchers at UCLA have created an edible particle that helps make lab-grown meat, known as cultured meat, with more natural muscle-like texture using a process that could be scaled up for mass production.

Led by Amy Rowat, who holds UCLA’s Marcie H. Rothman Presidential Chair of Food Studies, the researchers have invented edible particles called microcarriers with customized structures and textures that help precursor muscle cells grow quickly and form muscle-like tissues. Edible microcarriers could reduce the expense, time, and waste required to produce cultured meat with a texture that appeals to consumers. The results are published in the journal Biomaterials.

“Animal cells that can be coaxed to form tissues similar to meats could offer a protein source to a world facing food insecurity caused by threats ranging from epidemics to natural disasters,” said Rowat, who is an associate professor of integrative biology and physiology at the UCLA College. “Cultured meat products are not yet on the market in the U.S. and strategies to enable mass production are still emerging.”

Nanoengineers at the University of California San Diego have developed microscopic robots, called microrobots, that can swim around in the lungs, deliver medication and be used to clear up life-threatening cases of bacterial pneumonia.

In mice, the microrobots safely eliminated pneumonia-causing bacteria in the lungs and resulted in 100% survival. By contrast, untreated mice all died within three days after infection.

The results are published Sept. 22 in Nature Materials.

Stronger hurricanes that are re-energized by jet stream winds are twice as likely to cross the Atlantic and wreak havoc in Europe than weaker ones, new research has found.

Atlantic hurricanes generate international attention because of the destruction they can cause across North America and the Caribbean. Just days ago, ex-hurricane Fiona impacted Canada as one of their strongest storms on record. While lesser-known, these cyclones can also wreak havoc in Europe.

The question of why some hurricanes make it to Europe as ex-hurricanes while others don’t has been unclear. The scientists investigated this question by studying 180 ex-hurricanes over a 40-year period, finding that stronger hurricanes are far more likely to reach Europe, and that those encountering strong jet stream winds often re-intensify, helping them to move further east.

How a tiny marine invertebrate distinguishes its own cells from competitors’ bears striking similarities to the human immune system, according to a new study led by University of Pittsburgh School of Medicine researchers.

The findings, published now in Proceedings of the National Academy of Sciences, suggest that the building blocks of our immune system evolved much earlier than previously thought and could help improve understanding of transplant rejection, one day guiding development of new immunotherapies.

“For decades, researchers have wondered whether self-recognition in a marine creature called Hydractinia symbiolongicarpus was akin to the processes that control whether a piece of skin can be successfully grafted from one person to another,” said senior author Matthew Nictora, Ph.D., assistant professor of surgery and immunology at the Thomas E. Starzl Transplantation Institute. “Our study shows for the first time that a special group of proteins called the immunoglobulin superfamily— which are important for adaptive immunity in mammals and other vertebrates—are found in such a distantly-related animal.”

Is science destined to crack the code of—and how would we even go about it?

Jülich researchers have been able to demonstrate an exotic electronic state, so-called Fermi Arcs, for the first time in a 2D material. The surprising appearance of Fermi arcs in such a material provides a link between novel quantum materials and their respective potential applications in a new generation of spintronics and quantum computing. The results have recently been published in Nature Communications.

The newly detected Fermi arcs represent special—arc-like—deviations from the so-called Fermi surface. The Fermi surface is used in condensed matter physics to describe the momentum distribution of electrons in a metal. Normally, these Fermi surfaces represent closed surfaces. Exceptions such as the Fermi arcs are very rare and often are associated with exotic properties like superconductivity, negative magnetoresistance and anomalous quantum transport effects.

Today’s technology challenge is to develop the “on-demand” control of physical properties in materials. However, such experimental tests have been largely limited to bulk materials and are key grand challenges in condensed matter science. With its groundbreaking paradigm, the findings present a promising new frontier for quantum control of topological states in low-dimensional systems by external means—the external magnetic field that offers unprecedented capabilities on 2D materials for artificial intelligence as well as future information processing.