Lifeboat Foundation

Traumatic brain injuries might have faded from the headlines since the NFL reached a $765 million settlement for concussion-related brain injuries, but professional football players aren’t the only ones impacted by these injuries. Each year, between 2 million and 3 million Americans suffer from traumatic brain injuries—from elderly people who fall and hit their head, to adolescents playing sports or falling out of trees, to people in motor vehicle accidents.

There are currently no treatments to stop the long-term effects of a traumatic brain injury (TBI), and accurate diagnosis requires a visit to a medical center for a CT scan or MRI, both of which involve large, expensive equipment.

UC San Diego bioengineering Professor Ester Kwon, who leads the Nanoscale Bioengineering research lab at the Jacobs School of Engineering, aims to change that. Kwon’s team is developing nanomaterials—materials with dimensions on the nanometer scale—that could be used to diagnose traumatic brain injury on the spot, be it a sports field, the scene of a car accident, or a clinical setting. They’re also engineering nanoparticles that could target the portion of the patient’s brain that was injured, delivering specific therapeutics to treat the injury and improve the patient’s long-term quality of life.

Using human brain organoids, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Sanford Consortium, has shown how the SARS-CoV-2 virus that causes COVID-19 infects cortical neurons and specifically destroys their synapses — the connections between brain cells that allow them to communicate with each other.

The findings, published in the November 3, 2022 issue of PLOS Biology, also report that the antiviral drug sofosbuvir, already an approved treatment for hepatitis C, effectively inhibited SARS-CoV-2 replication and reversed neuronal alterations in infected brain organoids.

“Vaccines and emerging treatments have reduced the health consequences of COVID-19 in most patients,” said senior study author Alysson R. Muotri, PhD, professor in departments of Pediatrics and Cellular and Molecular at UC San Diego School of Medicine. “But the phenomenon of Long COVID, characterized by persisting symptoms that include neurological impairment, remains poorly understood and without any specific remedy.

Los Alamos National Laboratory researchers have developed a novel method for comparing neural networks that looks into the “black box” of artificial intelligence to help researchers comprehend neural network behavior. Neural networks identify patterns in datasets and are utilized in applications as diverse as virtual assistants, facial recognition systems, and self-driving vehicles.

“The artificial intelligence research community doesn’t necessarily have a complete understanding of what neural networks are doing; they give us good results, but we don’t know how or why,” said Haydn Jones, a researcher in the Advanced Research in Cyber Systems group at Los Alamos. “Our new method does a better job of comparing neural networks, which is a crucial step toward better understanding the mathematics behind AI.”

To foster empathy in conversation, scientists at Kyoto University developed a shared-laughter AI system that reacts properly to human laughter.

What makes something hilarious has baffled philosophers and scientists since at least the time of inquiring minds like Plato. The Greeks believed that feeling superior at others’ expense was the source of humor. Sigmund Freud, a German psychologist, thought humor was a means to let off pent-up energy. In order to make people laugh, US comedian Robin Williams tapped his anger at the absurd.

No one appears to be able to agree on the answer to the question, “What’s so funny?” So picture attempting to train a robot to laugh. But by creating an AI that gets its signals from a shared laughing system, a team of researchers at Kyoto University in Japan is trying to do that. The researchers describe their novel technique for creating a funny bone for the Japanese robot ‘Erica’ in the journal Frontiers in Robotics and AI.

Is a Gerontologist and Clinical Social Worker on a mission to rethink aging, longevity & mental health.

Ms. Anderson was also the former lead singer of the American Rock group, The Donnas (https://en.wikipedia.org/wiki/The_Donnas), where she was the lead vocalist for 20 years, performing throughout the U.S., as well as internationally, and had performances / appearances on major network shows including Saturday Night Live, David Letterman and Late Night with Conan O’Brien.

Continue reading “Brett Anderson, MSG, MSW — Journey From Rock Musician To Rethinking Aging, Longevity & Mental Health” »

Coca leaf and cocaine may soon join alcohol, tobacco, caffeine and cannabis as legally regulated drugs.

Colombia’s new government wants to legalize coca leaf and cocaine. So does Peru. And Bolivia has been on that path since 2012.

The discovery of Gaia BH1, a binary system containing what is likely the closest known black hole to Earth, is reported by astronomers in the U.S.

If you wake up early Sunday morning and see a small, bright object streaking through the sky, it could be a rocket that is being launched from the NASA Wallops Flight Facility in eastern Virginia.

NASA officials say the rocket may be visible from Delaware, Maryland, New Jersey, North Carolina, Pennsylvania, Virginia and West Virginia, along with Connecticut and lower New York state, shortly after liftoff — scheduled for 5:50 a.m. Sunday, Nov. 6.

The Northrop Grumman Antares rocket will be delivering supplies and science experiments to the International Space Station, NASA said. It will be the agency’s 18th resupply mission for the space station.

Bias in AI systems is proving to be a major stumbling block in efforts to more broadly integrate the technology into our society.

A new initiative that will reward researchers for finding any prejudices in AI systems could help solve the problem.

The effort is modeled on the bug bounties that software companies pay to cybersecurity experts who alert them of any potential security flaws in their products.