Lifeboat Foundation: Safeguarding Humanity
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Over the past 8.5 years, its predecessor, the K5, has successfully patrolled diverse locations across the US, contributing significantly to crime reduction and ensuring safety in various environments, claims the firm.

Knightscope, a prominent developer of autonomous security robots, has officially commenced the shipment of its highly anticipated 5th Generation K5 Autonomous Security Robot (ASR), the company announced in a press release.

This represents a significant milestone for the company and marks a thorough redesign to elevate the flagship ASR’s capabilities. Production is in full swing at Knightscope’s Silicon Valley Headquarters. It is proudly made in America, with machines ready to fulfill nationwide contracts.

Innovations with over 2.5 million hours of field operations

The K5v5 boasts a ground-up design, informed by over 2.5 million hours of field operations, delivering tangible results for real clients. Notable enhancements include a wider stance for a more stable propulsion system, raised camera elevation enabling near eye-level 4K video capture, a revamped battery architecture for improved performance, upgraded audio capabilities for broadcast messages, intercom, and public address, enhanced nighttime visibility with additional lighting, and a significant reduction in part count and assembly time. The redesign prioritizes serviceability and maintenance, ensuring seamless operation for clients.

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SpaceX is making significant progress in obtaining launch licenses, increasing their number of launches, and potentially extending the operational life of the Hubble Space Telescope through a rescue mission.

Questions to inspire discussion.

What progress is SpaceX making with the Starship launch?
—SpaceX is preparing for the third orbital Starship launch, with crews working to restore infrastructure and repair cracks at the launch site. They are also making design improvements and testing the deflector system.

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During a chemical reaction, molecules gain energy until they reach what’s known as the transition state — a point of no return from which the reaction must proceed.

MIT chemists have developed a computational model that can rapidly predict the structure of the transition state of a reaction (left structure), if it is given the structure of a reactant (middle) and product (right).

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Isaac arthur playlist.

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Space Coast Live provides 24/7 views of SpaceX and NASA launch operations in Florida including the new Starship pad at LC-39A. The Kennedy Space Center-based cameras are supplemented by Fleetcam, which provides views of recovery vessels in Port Canaveral.

Fleetcam is located at Rusty’s Seafood & Oyster Bar (https://www.rustysseafood.com/) in Port Canaveral, Florida. This stream has no audio commentary.

Our other livestreams!
Starbase Live: http://nsf.live/starbase.
McGregor Live: http://nsf.live/mcgregor

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Batteries that exploit quantum phenomena to gain, distribute and store power promise to surpass the abilities and usefulness of conventional chemical batteries in certain low-power applications. For the first time, researchers, including those from the University of Tokyo, take advantage of an unintuitive quantum process that disregards the conventional notion of causality to improve the performance of so-called quantum batteries, bringing this future technology a little closer to reality.

When you hear the word “quantum,” the physics governing the subatomic world, developments in quantum computers tend to steal the headlines, but there are other upcoming quantum technologies worth paying attention to. One such item is the which, though initially puzzling in name, holds unexplored potential for sustainable energy solutions and possible integration into future electric vehicles. Nevertheless, these new devices are poised to find use in various portable and low-power applications, especially when opportunities to recharge are scarce.

At present, quantum batteries only exist as laboratory experiments, and researchers around the world are working on the different aspects that are hoped to one day combine into a fully functioning and practical application. Graduate student Yuanbo Chen and Associate Professor Yoshihiko Hasegawa from the Department of Information and Communication Engineering at the University of Tokyo are investigating the best way to charge a quantum battery, and this is where time comes into play. One of the advantages of quantum batteries is that they should be incredibly efficient, but that hinges on the way they are charged.

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Prior studies have linked high blood cholesterol levels to various cancers, including colorectal cancers. However, it hasn’t been clear that lowering cholesterol can prevent colorectal cancers. Now, researchers at Weill Cornell Medicine have found in mice hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol. Their finding points to the possibility of using cholesterol-lowering drugs to prevent or treat such tumors.

The findings are published in Nature Communications in an article titled, “Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis.”

“The metabolic and signaling pathways regulating aggressive mesenchymal colorectal cancer (CRC) initiation and progression through the serrated route are largely unknown,” the researchers wrote. “Although relatively well characterized as BRAF mutant cancers, their poor response to current targeted therapy, difficult preneoplastic detection, and challenging endoscopic resection make the identification of their metabolic requirements a priority. Here, we demonstrate that the phosphorylation of SCAP by the atypical PKC (aPKC), PKCλ/ι promotes its degradation and inhibits the processing and activation of SREBP2, the master regulator of cholesterol biosynthesis.”

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