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The most common screening test for prostate cancer — a measure of prostate-specific antigen, or PSA, levels — so often suggests cancer where there is none that clinical guidelines no longer recommend the test for men over 70 and leave the decision up to younger patients.

Scientists at Stanford Medicine and their collaborators aim to make PSA screening more accurate — by calibrating PSA levels to each man’s genetics. Applying this type of personalization could significantly reduce overdiagnosis and better predict aggressive disease. Their research was published June 1 in Nature Medicine.

In addition to the regular blood-based PSA test, such personalized screening would require a germline genetic test, typically done on saliva, blood or cheek swab samples, to look for inherited genetic variants that affect PSA levels.

This Jenner-active AI is frighteningly good.

Our sci-fi-inspired fears of artificial intelligence replicating us may not be unfounded: Meta set off alarm bells after introducing an AI chatbot named Billie that resembled Kendall Jenner so closely, they thought it was the model herself, the NY Post reports.

A video introducing the creepy Kardashian doppelganger is currently eliciting screams across the web.

In this episode, Max and Daniel sit down with the renowned Aubrey de Grey to discuss the connection between life extension and cryonics. They cover a wide range of topics, diving into the latest breakthroughs and obstacles in both fields.

In this captivating conversation, they explore:

-The current state of rejuvenation technologies.
–Recent advances in longevity research over the past decade.
–Challenges still facing life extension science.
–Perspectives on achieving longevity escape velocity.
–Progress in robust mouse rejuvenation experiments.
–Aubrey de Grey’s journey into the world of cryonics.
–Tanya Jones’s new cryonics venture, Keinice.
–Innovative cryopreservation techniques using helium persufflation.
–The importance of cryonics vs life extension.
–The potential for cryonics to become mainstream.
–The search for major donors to support cryonics research.
–And much more!

As always, you can find Max and Daniel over at the Cryosphere Cryonics discord server: https://discord.gg/cryosphere.

You can listen to the audio only version at our website or any of your favorite podcast apps:
https://www.cryonicsunderground.com/1510453/12638348-aubrey-…-extension.

Visit Aubrey’s new organization The Longevity Escape Velocity Foundation https://www.levf.org/

OpenAI CEO Sam Altman has announced internally that the company is targeting $1.3 billion in annual revenue, according to The Information.

That’s 30 percent more than the $1 billion in annual revenue leaked over the summer, which was already said to have exceeded investor expectations. The new figure suggests more than $100 million in monthly revenue.

The biggest revenue driver is subscriptions to ChatGPT Plus. Last year, without the ChatGPT Plus offering, OpenAI had revenue of only $28 million, with a loss of $540 million, according to The Information.