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Blog – Page 2952

Scientists at St. Anna Children’s Cancer Research Institute and the Eberhard Karls University of Tübingen have shown that immunotherapy after stem cell transplantation effectively combats certain nerve tumors in children. Crucially, stem cells from a parent provide children with a new immune system that responds much better to immunotherapies. These results of an early clinical trial were published in the prestigious Journal of Clinical Oncology.

Childhood tumors of the nervous system, known as neuroblastomas, are associated with an unfavorable prognosis if the tumor is classified as a high-risk type. The chances are particularly poor for patients in the relapsed stage. In this case, immunotherapy following stem cell transplantation is now associated with in a substantial proportion of the patients included in a recent study. Compared to an earlier study the survival rate was increased.

“After the transplantation of from a parent, the patients are equipped with a new immune system. This enables a better immune response to the subsequent immunotherapy and clearly improves the outcome,” explains Prof. Ruth Ladenstein, MD, head of the Studies & Statistics group for Integrated Research and Projects (S2IRP) at St. Anna Children’s Cancer Research Institute and professor at the Department of Pediatrics and Adolescent Medicine at MedUni Vienna, who played a key role as co-first author.

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NASA has reestablished connection with Voyager 2 after a tense two weeks of not hearing anything from the probe. On July 21st, the agency lost contact with Voyager 2 following a series of planned commands that mistakenly pointed it two degrees away from our planet. While it is scheduled to automatically reset its orientation on October 15th, it’s not surprising that NASA scientists didn’t just wait for that date to know whether the spacecraft is still running. Voyager 2 was launched way back in 1977, and it’s one of the only two probes sending us back valuable data on interstellar space.

For a few days after July 21st, NASA wasn’t even sure what the spacecraft’s condition was. It wasn’t until August 1st that multiple ground antennas from the Deep Space Network (DSN) were able to detect a carrier signal from the probe. A carrier signal is what a spacecraft uses to beam data back to the ground, but NASA said the one DSN detected was too weak to be able to transmit any information. Still, it was enough to confirm that Voyager 2 was still working and that it hadn’t deviated from its trajectory.

Instead of simply waiting for October, Voyager’s ground team decided to take action. They concocted a plan to “shout” a command to the spacecraft across over 12.3 billion miles of space using the DSN, telling it to turn its antenna back to Earth. The whole process illustrated just how vast outer space truly is: It took 18.5 hours for that message to reach the probe, and another 18.5 hours for NASA to start receiving science and telemetry data again, indicating that Voyager 2 had received the command.

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On the twelfth challenge: Suppose that in the next decade or two, we meet all the engineering challenges in a single system. Will we then have a conscious AI systems? Not everyone will agree that we do. But if someone disagrees, we can ask once again: what is the X that is missing? And could that X be built into an AI system?

My conclusion is that within the next decade, even if we don’t have human-level artificial general intelligence, we may well have systems that are serious candidates for consciousness. There are many challenges on the path to consciousness in machine learning systems, but meeting those challenges yields a possible research program toward conscious AI.

I’ll finish by reiterating the ethical challenge.4 I’m not asserting that we should pursue this research program. If you think conscious AI is desirable, the program can serve as a sort of roadmap for getting there. If you think conscious AI is something to avoid, then the program can highlight paths that are best avoided. I’d be especially cautious about creating agent models. That said, I think it’s likely that researchers will pursue many of the elements of this research program, whether or not they think of this as pursuing AI consciousness. It could be a disaster to stumble upon AI consciousness unknowingly and unreflectively. So I hope that making these possible paths explicit at least helps us to think about conscious AI reflectively and to handle these issues with care.

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HBP researchers from Germany performed detailed cytoarchitectonic mapping of distinct areas in a human cortical region called frontal operculum and, using connectivity modelling, linked the areas to a variety of different functions including sexual sensation, muscle coordination as well as music and language processing.

The study contributes to the further unravelling of the relationship of the human brain’s structure with function, and is the first proof-of-concept of structural and functional connectivity analysis of the frontal operculum. The newly identified cytoarchitectonic areas have been made publicly available as part of the Julich-Brain Atlas on the EBRAINS platform, inviting for future research to further characterise this brain region.

Based on cell-body stained histological sections in ten postmortem brains (five females and five males), HBP researchers from Heinrich Heine University Düsseldorf and Research Centre Jülich identified three new areas in the frontal operculum: Op5, Op6 and Op7. Each of these areas had a distinct cytoarchitecture. Connectivity modelling showed that each area could be ascribed a distinct functional role.

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Deep space is a hostile environment for humans, which makes the long journey to Mars a serious stumbling block for manned missions. A nuclear-powered rocket could slash the journey time, and NASA has announced plans to test the technology by 2027 at the latest.

Most spacecraft to date have used chemical rockets packed with fuel and oxidizer, which rely on combustion to propel them through space. A nuclear-powered rocket would instead use a fission reactor to heat liquid hydrogen to very high temperatures and then blast it out the back of the spacecraft.

These kinds of engines could be up to three times more efficient than those in conventional rockets, and could cut the time to transit from Earth to Mars from roughly seven months to as little as six weeks. NASA has teamed up with DARPA to make the idea a reality, signing a deal with defense contractor Lockheed Martin to launch a working prototype into space as early as 2025.

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When Albert Einstein famously said “God does not play dice with the universe” he wasn’t objecting to the idea that randomness exists in our everyday lives.

What he didn’t like was the idea that randomness is so essential to the laws of physics, that even with the most precise measurements and carefully controlled experiments there would always be some level at which the outcome is effectively an educated guess. He believed there was another option.

This video discusses how probability is determined in quantum mechanics. Let’s play some dice with the universe and talk about it.

Join Katie Mack, Perimeter Institute’s Hawking Chair in Cosmology and Science Communication, over 10 short forays into the weird, wonderful world of quantum science. Episodes are published weekly, subscribe to our channel so you don’t miss an update.

Continue reading “Quantum 101 Episode 6: Quantum Probability Explained” | >