Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 2843

1 Department of Biotechnology, School of Science, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, 530,045, India; 2 Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61,801, USA

Correspondence: Sireesha V Garimella; Pankaj Chaturvedi, Email [email protected]; [email protected]

Abstract: Cancer continues to rank among the world’s leading causes of mortality despite advancements in treatment. Cancer stem cells, which can self-renew, are present in low abundance and contribute significantly to tumor recurrence, tumorigenicity, and drug resistance to various therapies. The drug resistance observed in cancer stem cells is attributed to several factors, such as cellular quiescence, dormancy, elevated aldehyde dehydrogenase activity, apoptosis evasion mechanisms, high expression of drug efflux pumps, protective vascular niche, enhanced DNA damage response, scavenging of reactive oxygen species, hypoxic stability, and stemness-related signaling pathways. Multiple studies have shown that mitochondria play a pivotal role in conferring drug resistance to cancer stem cells, through mitochondrial biogenesis, metabolism, and dynamics. A better understanding of how mitochondria contribute to tumorigenesis, heterogeneity, and drug resistance could lead to the development of innovative cancer treatments.

Read more | >

Russia’s space agency on Tuesday said that the crew stuck on the International Space Station because of a damaged capsule were now expected to return to Earth in September, a year after they first launched into orbit.

Russian cosmonauts Dmitry Petelin and Sergei Prokopyev and NASA astronaut Frank Rubio flew to the ISS in September 2022 aboard a Soyuz MS-22 capsule.

They were scheduled to return home in the same spacecraft, but it began leaking coolant in mid-December after being hit by what US and Russian space officials believe was a tiny space rock.

Read more | >

A team of computer scientists at the University of Massachusetts Amherst, led by Emery Berger, recently unveiled a prize-winning Python profiler called Scalene. Programs written with Python are notoriously slow—up to 60,000 times slower than code written in other programming languages—and Scalene works to efficiently identify exactly where Python is lagging, allowing programmers to troubleshoot and streamline their code for higher performance.

There are many different —C++, Fortran and Java are some of the more well-known ones—but, in recent years, one language has become nearly ubiquitous: Python.

“Python is a ‘batteries-included’ language,” says Berger, who is a professor of computer science in the Manning College of Information and Computer Sciences at UMass Amherst, “and it has become very popular in the age of data science and because it is so user-friendly.” The comes with libraries of easy-to-use tools and has an intuitive and readable syntax, allowing users to quickly begin writing Python code.

Read more | >

WEST LAFAYETTE, Ind. – Researchers at Purdue University are advancing the world of robotics and autonomy with their patent-pending method that improves on traditional machine vision and perception.

Zubin Jacob, the Elmore Associate Professor of Electrical and Computer Engineering in the Elmore Family School of Electrical and Computer Engineering, and research scientist Fanglin Bao have developed HADAR, or heat-assisted detection and ranging. Their research was featured on the cover of the July 26 issue of the peer-reviewed journal Nature. A video about HADAR is available on YouTube. Nature also has released a podcast episode that includes an interview with Jacob.

Jacob said it is expected that one in 10 vehicles will be automated and that there will be 20 million robot helpers that serve people by 2030.

Read more | >

If your mother says she loves you: check it.

A couple weeks ago, I asked Vergecast.

What I was not expecting was for so many people to send me versions of a video that shows a banana getting stitches in a robotic surgery device, with the captions claiming that the surgery is being done remotely over 5G. This video has had an … More.

Meet Dr. Kais Rona, who is as befuddled by the lie appended to his video as anyone else.

Continue reading “No, they did not do surgery on a banana over 5G” | >

NotebookLM is a neat research tool with some big ideas. It’s still rough and new, but it feels like Google is onto something.

What if you could have a conversation with your notes? That question has consumed a corner of the internet recently.

Google’s version of this is called NotebookLM. It’s an AI-powered research tool that is meant to help you organize and interact with your own notes. (Google originally announced it earlier this year as Project Tailwind but quickly changed the name.) Right now, it’s really just a… More.

NotebookLM gives you a chatbot for your personal docs, and it’s already pretty helpful.

Continue reading “Google’s AI-powered note-taking app is the messy beginning of something great” | >

Google Flights today is releasing a new feature that will help travelers better determine the right time to book. Rolling out this week, the company is debuting new insights that will leverage historical trend data that lets consumers see when prices have typically been lowest to their chosen destination on their selected dates.

The addition aims to help consumers answer the question as to whether it’s better to book their flight now or wait for lower prices.

For example, Google explains, the new insights could tell users that the cheapest time to book their trip is currently two months prior to departure or that, typically, prices for their trip have generally declined closer to the date of departure. With this new understanding of whether or not they’re getting the best deal, consumers may chose to either book immediately or wait for a better price.

Read more | >