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In the grand sweep of scientific history, revolutions in thought are often born from a simple yet unsettling realization: that the fundamental nature of reality is not what we once assumed it to be. In the 20th century, physics was shaken by the twin cataclysms of relativity and quantum mechanics, revealing that space and time themselves were malleable, that particles could exist in superpositions, and that observation played a fundamental role in shaping what we call reality.

Imagine a scale that ranks civilizations not by their borders or technology, but by the sheer energy they command— some spanning entire galaxies. Join us as we explore the Kardashev Scale, the ultimate measure of cosmic power.

Watch my exclusive video Big Alien Theory https://nebula.tv/videos/isaacarthur–… Nebula using my link for 40% off an annual subscription: https://go.nebula.tv/isaacarthur Get a Lifetime Membership to Nebula for only $300: https://go.nebula.tv/lifetime?ref=isa… Use the link gift.nebula.tv/isaacarthur to give a year of Nebula to a friend for just $30. Visit our Website: http://www.isaacarthur.net Join Nebula: https://go.nebula.tv/isaacarthur Support us on Patreon: / isaacarthur Support us on Subscribestar: https://www.subscribestar.com/isaac-a… Facebook Group: / 1,583,992,725,237,264 Reddit: / isaacarthur Twitter: / isaac_a_arthur on Twitter and RT our future content. SFIA Discord Server: / discord Credits: The Kardashev Scale & Population Episode 486; February 13, 2025 Written, Produced & Narrated by: Isaac Arthur Editors: Ludwig Luska Graphics: Fishy Tree, Jeremy Jozwik, Ken York YD Visual Select imagery/video supplied by Getty Images Music Courtesy of Epidemic Sound http://epidemicsound.com/creator Phase Shift, “Forest Night” Chris Zabriskie, “Unfoldment, Revealment”, “A New Day in a New Sector”, “Oxygen Garden” Stellardrone, “Red Giant”, “Billions and Billions“
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Credits:
The Kardashev Scale & Population.
Episode 486; February 13, 2025
Written, Produced & Narrated by: Isaac Arthur.
Editors: Ludwig Luska.
Graphics: Fishy Tree, Jeremy Jozwik, Ken York YD Visual.
Select imagery/video supplied by Getty Images.
Music Courtesy of Epidemic Sound http://epidemicsound.com/creator.
Phase Shift, \

On this episode of Cultivate Curiosity, our host Jacie takes us on a journey through a few spectacular upcoming astronomical events. From February’s dazzling planetary alignments and bright Venusian glow to March and April’s upcoming eclipses and meteor showers, we explore the science behind these celestial events and how to best view them. Whether you’re an avid stargazer or just looking up with curiosity, this episode will inspire you to keep your eyes on the sky!

A new blood test developed by researchers at Oregon Health & Science University (OHSU) shows promise for the early detection of pancreatic cancer, a disease notorious for its high mortality rates due to late diagnosis.

The test, named PAC-MANN, which stands for “protease activity-based assay using a magnetic nanosensor,” could provide a critical tool for doctors.

It can potentially lead to improved survival rates for patients diagnosed with pancreatic ductal adenocarcinoma (PDAC), the most prevalent and aggressive form of pancreatic cancer.

Aging is a natural process, but for centuries, humans have been searching for ways to slow it down or even reverse it. Recent advancements in stem cell research and regenerative medicine have given scientists unprecedented insights into aging and potential interventions. With breakthroughs in cellular therapy, gene editing, and tissue engineering, we are closer than ever to finding ways to rejuvenate the human body. But how close are we to reversing aging, and what challenges remain?

Stem cells are the body’s raw materials from which all other specialized cells are generated. They have the unique ability to divide and create identical copies of themselves (self-renewal) or differentiate into specialized cell types. However, as we age, our stem cells decline in both number and efficiency, contributing to tissue degeneration, slower healing, and an increased risk of age-related diseases.

Researchers have been investigating how stem cells can be manipulated to repair damaged tissues, regenerate organs, and potentially reverse signs of aging. By harnessing stem cells, scientists aim to restore youthful function in various tissues and organs, offering promising anti-aging therapies.