Lifeboat Foundation

Nearly 270,000 people in the United States are diagnosed with breast cancer each year.

According to the Susan G. Komen Foundation, about 70%–80% of these individuals experience estrogen receptor-positive (ER+) breast cancer, where cancer cells need estrogen to grow. In terms of treatment, this presence of hormone receptors provides a nice handle for targeting tumors, say with therapies that knock out the tumor cell’s ability to bind to estrogen and prevent remaining breast cancer cells from growing.

However, even if treated successfully, on average, one in five individuals with ER+ breast cancer experience a late recurrence when dormant tumor cells in distant parts of the body, such as the bone marrow, reactivate anywhere from five to over 20 years after initial treatment.

Roboticists have developed many advanced systems over the past decade or so, yet most of these systems still require some degree of human supervision. Ideally, future robots should explore unknown environments autonomously and independently, continuously collecting data and learning from this data.

Researchers at Carnegie Mellon University recently created ALAN, a robotic agent that can autonomously explore unfamiliar environments. This robot, introduced in a paper pre-published on arXiv and set to be presented at the International Conference of Robotics and Automation (ICRA 2023), was found to successfully complete tasks in the real-world after a brief number of exploration trials.

Continue reading “A robot that can autonomously explore real-world environments” »

FallenKingdomReads’ Beginner’s Guide to The Dark Tower by Stephen King

The Dark Tower is a series of novels written by the American author Stephen King. The series is a blend of several genres, including dark fantasy, horror, and western. The series follows the journey of the protagonist, Roland Deschain, as he seeks the Dark Tower, a mythical structure that is said to be the center of all universes.

Making living cells blink fluorescently like party lights may sound frivolous. But the demonstration that it’s possible could be a step toward someday programming our body’s immune cells to attack cancers more effectively and safely.

That’s the promise of the field called synthetic biology. While molecular biologists strip cells down to their component genes and molecules to see how they work, synthetic biologists tinker with cells to get them to perform new feats — discovering new secrets about how life works in the process. In this episode, Steven Strogatz talks with Michael Elowitz, a professor of biology and bioengineering at the California Institute of Technology and a Howard Hughes Medical Institute Investigator.

In a historic achievement, University of Rochester researchers have created a superconducting material at both a temperature and pressure low enough for practical applications.

“With this material, the dawn of ambient superconductivity and applied technologies has arrived,” according to a team led by Ranga Dias, an assistant professor of mechanical engineering and physics. In a paper in Nature, the researchers describe a nitrogen-doped lutetium hydride (NDLH) that exhibits superconductivity at 69 degrees Fahrenheit (20.5 degrees Celsius) and 10 kilobars (145,000 pounds per square inch, or psi) of pressure.

Continue reading “Viable superconducting material created at low temperature and low pressure” »

Human enhancement has long been depicted as having the potential to help but also harm humanity. Brian Greene talks with Neuroscientists Takao Hensch, John Krakauer and Entrepreneur Brett Wingeier about their experiments using brain plasticity to heal illness, improve cognitive and athletic performance. They also raise warning flags about the race to build a more perfect human.

This program is part of the Big Ideas series, supported by the John Templeton Foundation.

Continue reading “Rewiring the Brain: The Promise and Peril of Neuroplasticity” »

Companies could one day make superconductive quantum computer chips that function at room temperature thanks to a new material from researchers in the US. Ranga Dias from the University of Rochester and colleagues made a material superconductive at 21°C and pressures less than 1% of those used for existing high-temperature superconductors. ‘The most exciting part is the pressure,’ Dias tells Chemistry World. ‘Even I didn’t think this was possible.’

Together with Ashkan Salamat’s team at the University of Nevada, Las Vegas, the scientists say that electrical resistance in their nitrogen-doped lutetium hydride falls to zero at room temperature. Making room-temperature zero-resistance materials is a chemistry ‘holy grail’ and could fight climate change by reducing the 5% of electricity lost as heat while flowing through the grid.

However, Dias and Salamat’s team hasn’t been able to fully confirm the new material’s structure. As hydrogen atoms are so small they don’t easily diffract the x-rays used to work out the material’s composition. And this is an important reservation, considering the publisher of the team’s previous high-temperature superconductor paper retracted it.

Scientists are abandoning conventional thinking to search for extraterrestrial creatures that bear little resemblance to Earthlings.