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Scientists have grown a tiny brain-like organoid out of human stem cells, hooked it up to a computer, and demonstrated its potential as a kind of organic machine learning chip, showing it can quickly pick up speech recognition and math predictions.

As incredible as recent advances have been in machine learning, artificial intelligence still lags way behind the human brain in some important ways. For example, the brain happily learns and adapts all day long on an energy budget of about 20 watts, where a comparably powerful artificial neural network needs about 8 million watts to achieve anything remotely comparable.

What’s more, the human brain’s neural plasticity, its ability to grow new nervous tissue and expand existing connective channels, has granted it an ability to learn from noisy, low-quality data streams, with minimal training and energy expenditure. What AI systems accomplish with brute force and massive energy, the brain achieves with an effortless elegance. It’s a credit to the billions of years of high-stakes trial and error that delivered the human brain to the state it’s in today, in which it’s chiefly used to watch vast numbers of other people dancing while we’re on the toilet.

Tesla is making progress with Cybertruck production, expanding orders and discussing engineering details and battery options, while also facing production challenges and changes in market demand.

Questions to inspire discussion.

What is Tesla doing with Cybertruck production?
—Tesla is expanding Cybertruck orders and discussing engineering details and battery options, while also facing production challenges and changes in market demand.

➤ Tesla teases a number of new features coming soon ➤ Bernstein calls TSLA short their best idea for 2024 ➤ Tesla China sales and production ➤ Model Y standard range sells out ➤ Tesla executives meet in Thailand ➤ Model Y becomes second best-selling car in US ➤ Tesla adds pre-qualifying finance option ➤ Cybertruck discussion from reviewers: https://youtu.be/8_aE58AMIw0 ➤ Calendar 0:00 TSLA 0:25 Bernstein recommends TSLA short 3:02 New features 7:25 China numbers 10:45 Model Y China 11:26 Thailand 12:26 Model Y US 13:11 Pre-qualification 13:38 Cybertruck reviewers 14:33 Calendar X:

Tesla is pushing the boundaries of AI and supercomputing with the development of Dojo 2, aiming to build the world’s biggest supercomputer by the end of next year, and setting high goals for performance and cost efficiency.

Questions to inspire discussion.

Who is leading Tesla’s DOJO supercomputer project?
—Peter Bannon is the new leader of Tesla’s DOJO supercomputer project, replacing the previous head, Ganesh Thind.

Tesla’s Giga Texas factory is not only expanding production capacity for the Cybertruck, but also hinting at the development of a $25K compact car and showcasing innovative and advanced manufacturing processes.

Questions to inspire discussion.

What vehicles is Giga Texas producing?
—Giga Texas is producing the Cybertruck, Model Y, and a new $25K compact car.

Tesla’s new Cybertruck launch and next generation vehicle will be game-changing, with innovations in materials, manufacturing processes, and affordability.

Questions to inspire discussion.

What innovations does Tesla’s new Cybertruck bring?
—The Cybertruck introduces innovations in materials, manufacturing processes, and affordability, including a special ultra strong stainless steel alloy and a new manufacturing process called air bending.

SpaceX is making significant progress in the development and testing of the Starship, with the completion of roof and wall structures, installation of cryo pipe insulation, and advanced development of the booster in the Rocket Garden.

Questions to inspire discussion.

What progress has SpaceX made with the Starship?
—SpaceX has completed roof and wall structures, installed cryo pipe insulation, and advanced development of the booster in the Rocket Garden.

Mini brains grown in a lab from stem cells spontaneously developed rudimentary eye structures, scientists reported in a fascinating paper in 2021.

On tiny, human-derived brain organoids grown in dishes, two bilaterally symmetrical optic cups were seen to grow, mirroring the development of eye structures in human embryos.

This incredible result will help us to better understand the process of eye differentiation and development, as well as eye diseases.

A team of chemists, microbiologists and physicists at the University of Cambridge in the U.K. has developed a way to use solid-state nanopores and multiplexed DNA barcoding to identify misfolded proteins such as those involved in neurodegenerative disorders in blood samples. In their study, reported in the Journal of the American Chemical Society, the group used multiplexed DNA barcoding techniques to overcome problems with nanopore filtering techniques for isolating harmful oligomers.

Prior research has shown that the presence of harmful oligomers in the brain can lead to misfolding of proteins associated with neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease. Medical researchers have been looking for a way to detect them in the blood as a way to diagnose neurodegenerative disease and to track the progression once it has been confirmed.

Unfortunately, finding them in complex mixtures such as blood has proven to be a daunting task. One approach has shown promise—using sensors—but to date, they cannot track target oligomers as they speed through customizable solid-state nanopore sensors. In this new effort, the research team overcame this problem by using customizable DNA nanostructures.