Lifeboat Foundation

Alchemy had its golden age in the 17th century, when it counted Isaac Newton and Robert Boyle among its adherents.

This groundbreaking study, which was published as the cover article in the journal Science, not only sheds light on our evolutionary history but also paves the way for a future where physicians could more accurately assess a patient’s likelihood of suffering from ailments like back pain or arthritis later in life.

“Our research is a powerful demonstration of the impact of AI in medicine, particularly when it comes to analyzing and quantifying imaging data, as well as integrating this information with health records and genetics rapidly and at large scale,” said Vagheesh Narasimhan, an assistant professor of integrative biology as well as statistics and data science, who led the multidisciplinary team of researchers, to provide the genetic map of skeletal proportions.

Raman spectroscopy—a chemical analysis method that shines monochromatic light onto a sample and records the scattered light that emerges—has caused frustration among biomedical researchers for more than half a century. Due to the heat generated by the light, live proteins are nearly destroyed during the optical measurements, leading to diminishing and non-reproducible results. As of recently, however, those frustrations may now be a thing of the past.

A group of researchers with the Institute for Quantum Sciences and Engineering at Texas A&M University and the Texas A&M Engineering Experiment Station (TEES) have developed a new technique that allows low-concentration and low-dose screenings of protein-to-ligand interactions in physiologically relevant conditions.

Titled thermostable-Raman-interaction-profiling (TRIP), this new approach is a paradigm-shifting answer to a long-standing problem that provides label-free, highly reproducible Raman spectroscopy measurements. The researchers published their findings in the Proceedings of the National Academy of Sciences.

A new neuroimaging study has found that individuals who consumed their first alcoholic drink before the age of 18 had weaker connections in the brain’s cognitive control network compared those who consumed their first alcoholic drink after the age of 18. This suggests that starting to drink alcohol at a young age might make this brain network less effective. The study was published in Psychiatry Research: Neuroimaging.

Although the adverse effects of alcohol consumption and related long-term health risks are well known, it is estimated that 30% of youth in the United States use alcohol by the eighth grade. 62% of adolescents report drinking their first alcoholic drink by the time they graduate from high school, around 18 years of age.

Studies have found that individuals who start using alcohol earlier are more likely to develop alcohol-related problems later in life. Individuals who drink their first alcoholic drink earlier are also more likely to get drunk for the first time at an earlier age. They are also more likely to participate in binge drinking i.e., to consume more than 5 standard drinks for men or more than 4 for women on a single occasion.

Jean Housen/Wikimedia Commons.

Researchers have uncovered valuable information about how these ancient societies were organized by analyzing ancient human DNA from a site in Gurgy ‘les Noisats,’ France, dating back to 7,000 years.

Scientists identify protein snippets made by extinct hominins.

A cutting-edge practice by two Vanderbilt researchers that enhances light in nanoscale structures could help in the detection of diseases like cancer.

The work by Justus Ndukaife, assistant professor of electrical engineering, and Sen Yang, a recent Ph.D. graduate from Ndukaife’s lab in Interdisciplinary Materials Science under Ndukaife, was published in Light: Science & Applications.

In their paper, they show how an engineered nanostructured surface—quasi-BIC dielectric metasurface—can be used to trap micro and sub-micron particles within seconds, which they say helps in the transport of analytes to biosensing surfaces. The metasurface can also serve as a sensor to detect the aggregated particles or molecules, and can be used to enhance fluorescence or Raman signals from the molecules, thereby boosting detection sensitivity, according to the researchers.

Dismantling the belief in a static universe, Edwin Hubble’s revolutionary observations in the 1920s laid the groundwork for our understanding of a continually expanding cosmos. However, we must seek to reconcile this theory with observations that are consistent with a non-expanding universe, writes Tim Anderson.

You have been taught that the universe began with a Big Bang, a hot, dense period about 13.8 billion years ago. And the reason we believe this to be true is because the universe is expanding and, therefore, was smaller in the past. The Cosmic Microwave Background is the smoking gun for the Big Bang, the result of a reionization of matter that made the universe transparent about 300–400,000 years after the Big Bang.

How did we go from Einstein modifying his equations to keep the universe static and eternal, which he called the biggest blunder of his life, to every scientist believing that the universe had a beginning in 10 years? It all started with astronomer Edwin Hubble using the most powerful telescope at the time on Mount Wilson in California. At the time, in the 1920s, scientists believed that the Milky Way galaxy was the totality of the universe. Objects in the night sky like Andromeda that we now know are galaxies were called “nebulae”.

In a new study funded by a $3 million grant from the National Institutes of Health (NIH), University of Missouri researcher Kiho Lee, an associate professor in the College of Agriculture, Food and Natural Resources, will use gene editing to investigate the building blocks of disease.