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How we classify cancer and spot it in its earliest stages could need an urgent rethink: researchers have found that even some healthy women carry cells with the key hallmarks of breast cancer.

These cells are known as aneuploid cells, and have an abnormal number of chromosomes. They’re common in invasive breast cancer, and it’s thought the chromosome imbalance enables cancer to spread and evade the body’s immune defenses.

Now it appears aneuploid cells might also be present even when there’s no cancer in sight. The researchers, from the University of Texas and the Baylor College of Medicine in Texas, found them in breast tissue samples from 49 healthy women.

The melting point is one of the most important measurements of material properties, which informs potential applications of materials in various fields. Experimental measurement of the melting point is complex and expensive, but computational methods could help achieve an equally accurate result more quickly and easily.

A research group from Skoltech conducted a study to calculate the maximum of a high-entropy carbonitrides—a compound of titanium, zirconium, tantalum, hafnium, and niobium with carbon and nitrogen.

The results published in the Scientific Reports journal indicate that high-entropy carbonitrides can be used as promising materials for protective coatings of equipment operating under —high temperature, thermal shock, and chemical corrosion.

Engineers at Northwestern University have demonstrated quantum teleportation over a fiber optic cable already carrying Internet traffic. This feat, published in the journal Optica, opens up new possibilities for combining quantum communication with existing Internet infrastructure. It also has major implications for the field of advanced sensing technologies and quantum computing applications.

Quantum teleportation, a process that harnesses the power of quantum entanglement, enables an ultra-fast and secure method of information sharing between distant network users. Unlike traditional communication methods, quantum teleportation does not require the physical transmission of particles. Instead, it relies on entangled particles exchanging information over great distances.

Nobody thought it would be possible to achieve this, according to Professor Prem Kumar, who led the study. “Our work shows a path towards next-generation quantum and classical networks sharing a unified fiber optic infrastructure. Basically, it opens the door to pushing quantum communications to the next level.”

The International Renewable Energy Agency says breakthroughs like this, along with others such as solar panels that work at night or China’s flywheel energy storage project, are key to cutting back on dirty energy use and creating stronger and more reliable power systems.

“Further international cooperation is vital to deliver fit-for-purpose grids, sufficient energy storage and faster electrification, which are integral to move clean energy transitions quickly and securely,” Executive Director of the International Energy Agency Fatih Birol said in an IEA report.

This new way of storing energy could deliver cleaner, more affordable energy to cities, businesses, and homes. Researchers at Rice University believe it could be widely available in five to 10 years, making renewable energy more practical and accessible.

Large language models (LLMs), such as Open AI’s renowned conversational platform ChatGPT, have recently become increasingly widespread, with many internet users relying on them to find information quickly and produce texts for various purposes. Yet most of these models perform significantly better on computers, due to the high computational demands associated with their size and data processing capabilities.

To tackle this challenge, computer scientists have also been developing small language models (SLMs), which have a similar architecture but are smaller. These models could be easier to deploy directly on smartphones, allowing users to consult ChatGPT-like platforms more easily daily.

Researchers at Beijing University of Posts and Telecommunications (BUPT) recently introduced PhoneLM, a new SLM architecture for smartphones that could be both efficient and highly performing. Their proposed architecture, presented in a paper published on the arXiv preprint server, was designed to attain near-optimal runtime efficiency before it undergoes pre-training on text data.

Whether cells in the human body survive or die under stress depends, among other things, on their mitochondria. Scientists at the Faculty of Medicine at the University of Freiburg have now shown that a sudden stop in energy production in mitochondria prevents normal cell death or so-called apoptosis and instead triggers an inflammatory response. The results of this research were published in the journal Immunity.

“We found that mitochondria provide a kind of decision-making aid: they regulate whether a cell undergoes clean, silent apoptosis or releases pro-inflammatory messenger substances,” explains Prof. Dr. Olaf Groß, head of the study, a scientist at the Institute of Neuropathology at the Medical Center—University of Freiburg and a member of the Cluster of Excellence CIBSS—Center for Integrative Biological Signaling Studies at the University of Freiburg.

“This finding helps us to better understand how the body maintains a balance between cell protection and defense mechanisms. This could open up new avenues for the treatment of inflammatory diseases.”

Researchers discovered that the mRNA modification m6A triggers rapid degradation, regulating protein production. This breakthrough could inform drug development to manage protein-related diseases.

Messenger ribonucleic acids (mRNA) are like the architects of our bodies. They carry precise blueprints for building proteins, which are read and assembled by their cellular partners, the ribosomes. Proteins are essential for our survival, as they regulate cell division, bolster the immune system, and make our cells resilient against external threats.

Just like in real-world construction, some cellular blueprints require extra instructions—such as when a protein needs to be produced rapidly or when corrections are needed for a flawed design. In our bodies, this role is fulfilled by RNA modifications. These small chemical changes function like detailed annotations, offering additional guidance to specific parts of the mRNA for optimal protein production.