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A pressure of 3,000 bar is applied to the cold shock protein B of Bacillus subtilis in a small tube in the NMR spectroscopy laboratory at the University of Konstanz. This is roughly three times the water pressure at the deepest point of the ocean. The pressure is so intense that the highly dynamic protein shows structural features that would not be sufficiently visible under normal pressure. But why do scientists apply such high pressure, which does not occur anywhere else on our planet under natural conditions? The answer is: To study processes and properties that are too volatile to be observed under normal conditions.

“This high pressure allows us to make states visible that actually do exist at 1 bar, but which we can only observe directly at 3,000 bar”, explains Frederic Berner, University of Konstanz. Literally “under high pressure”, the doctoral researcher investigates the properties of a protein determined by its structure, and how changes in the structure in turn influence its properties. In the research group Physical Chemistry and Nuclear Magnetic Resonance at the University of Konstanz, led by Michael Kovermann, he recently implemented a new method for analyzing the structural properties of proteins at 3,000 bar with as little influence as possible from surrounding effects. The two researchers now present their new methodological approach in the journal Angewandte Chemie International Edition.

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A ‘cage of cages’ is how scientists have described a new type of porous material, unique in its molecular structure, that could be used to trap carbon dioxide and another, more potent greenhouse gas.

Synthesized in the lab by researchers in the UK and China, the material is made in two steps, with reactions assembling triangular prism building blocks into larger, more symmetrical tetrahedral cages – producing the first molecular structure of its kind, the team claims.

The resulting material, with its abundance of polar molecules, attracts and holds greenhouse gasses such as carbon dioxide (CO2) with strong affinity. It also showed excellent stability in water, which would be critical for its use in capturing carbon in industrial settings, from wet or humid gas streams.

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A 20-second video from inside a Chinese humanoid robot factory is causing some consternation today around social media. It shows a range of highly realistic-looking, partially skinned humanoids under construction.

The video, uploaded by user ‘meimei4515,’ is uncredited, but shows several moving androids with human-like hair and skin – in stark contrast to most of the general-purpose humanoids we’d normally cover, which are designed to look like robots, rather than trying to fool anyone.

Here, there are rows of pretty cyborg-ladies, disembodied heads on stands, fully human-like presenter types wearing shirts and pants, and a surreal tree of humanoid arms, flexing and twirling their white-fingered hands in concert. It looks for all the world like a grittier version of Westworld’s backstage workshop.

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The archaeological landscape is rarely static. Discoveries continuously shift our understanding of the past, forcing us to redraw the boundaries of what we thought was possible or likely. A recent find on ancient woodworkings at Kalambo Falls, Zambia, is a prime example – it introduces us to early hominin builders with unexpected skills, operating long before the rise of Homo sapiens.

The unique conditions at Kalambo Falls were instrumental in the extraordinary preservation of ancient woodworking artifacts.

The site’s lush vegetation, sustained by a reliable water source, provided the necessities of life, making it a consistently appealing location for various hominin species across vast stretches of time. This long-term occupation increased the likelihood of artifacts being left behind.

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