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84% of them are worried about it.

A new statistical tool developed by researchers at the University of Chicago improves the ability to find genetic variants that cause disease. The tool, described in a new paper published January 26, 2024, in Nature Genetics, combines data from genome-wide association studies (GWAS) and predictions of genetic expression to limit the number of false positives and more accurately identify causal genes and variants for a disease.

GWAS is a commonly used approach to identify genes associated with a range of human traits, including most common diseases. Researchers compare genome sequences of a large group of people with a specific disease, for example, with another set of sequences from healthy individuals. The differences identified in the disease group could point to genetic variants that increase risk for that disease and warrant further study.

Most human diseases are not caused by a single genetic variation, however. Instead, they are the result of a complex interaction of multiple genes, environmental factors, and host of other variables. As a result, GWAS often identifies many variants across many regions in the genome that are associated with a disease.

Organic-based optoelectronic technology is increasingly recognized as an energy-efficient solution for low-power indoor electronics and wireless IoT sensors. This is largely due to its superior flexibility and light weight compared to conventional silicon-based devices. Notably, organic photovoltaic cells (OPVs) and organic photodetectors (OPDs) are leading examples in this field.

OPVs have the remarkable ability to absorb energy and generate electricity even under very low light conditions, while OPDs are capable of capturing images. However, despite their potential, the development of these devices has thus far been conducted independently. As a result, they have not yet reached the level of efficiency necessary to be considered practical for next-generation, miniaturized devices.

A Korea Institute of Science and Technology (KIST) research team, led by Dr. Min-Chul Park and Dr. Do Kyung Hwang of the Center for Opto-Electronic Materials and Devices, Prof. Jae Won Shim and Prof. Tae Geun Kim of the School of Electrical Engineering at Korea University, Prof. JaeHong Park of the Department of Chemistry and Nanoscience at Ewha Womans University, have now developed an organic-based optoelectronic device.

According to a paper submitted for peer review on January 4th, 2024, Lethal Infection of Human ACE2-Transgenic Mice Caused by SARS-CoV-2-related Pangolin Coronavirus GX_P2V(short_3UTR), a new lab-created coronavirus has the potential to kill 100% of those infected with the virus within 8 days of infection.

The mice were genetically modified to express the human ACE2 receptor. This is the receptor responsible for allowing coronavirus to gain cellular entry. The lab infected mice with a coronavirus engineered from a strain found in pangolins. Pangolins are medium-sized animals growing to 12 — 30 inches in length and have the appearance of a scale-plated anteater.

Researchers monitored the mice for signs of infection by recording body weight, taking tissue samples, and monitoring for other symptoms. By the third day post-infection, tissue samples from the infected mice had a significant amount of viral RNA in the brain, eye, lung, and nasal tissue.

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Paper page: https://huggingface.co/papers/2401.14403 https://open-world-mobilemanip.github.io/ Deploying robots in open-ended unstructured environments such as homes has been a long-standing research problem.

The Rail Bus, a pioneering mode of transportation originating in Zhuzhou, China, is a groundbreaking discovery. Introduced by the Chinese manufacturer CRRC, this self-driving vehicle, resembling a train but without tracks, completed its inaugural journey in 2017. The Rail Bus seeks to revolutionise traditional concepts of buses, trains, and trams. The design of the Rail Bus was presented to the public in June 2023, and remarkably, within a span of fewer than five months, CRRC initiated testing on October 30, 2017. Covering a 3-kilometer route with stops at four stations in Zhuzhou, this marked a significant milestone in transportation evolution.

Imagine printing a table leg or a chair frame in minutes using liquid metal. Researchers from MIT have developed a new additive manufacturing technique that can do just that.

Their technique, called liquid metal printing (LMP), involves depositing molten aluminum along a predefined path into a bed of tiny glass beads. The aluminum quickly hardens into a 3D structure, ready to be used or further processed.

Embark on a greener maritime future with Crowley’s eWolf, the first all-electric tugboat in the US, setting sail to revolutionize sustainability on the seas.