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Researchers with the Department of Energy’s SLAC National Accelerator Laboratory, Stanford University and the DOE’s Lawrence Berkeley National Laboratory (LBNL) have grown a twisted multilayer crystal structure for the first time and measured the structure’s key properties. The twisted structure could help researchers develop next-generation materials for solar cells, quantum computers, lasers and other devices.

“This structure is something that we have not seen before—it was a huge surprise to me,” said Yi Cui, a professor at Stanford and SLAC and co-author of a paper published in Science describing the work. “A new quantum electronic property could appear within this three-layer twisted structure in future experiments.”

Researchers at the University of Augsburg and the University of Vienna have discovered co-existing magnetic skyrmions and antiskyrmions of arbitrary topological charge at room temperature in magnetic Co/Ni multilayer thin films. Their findings have been published in Nature Physics and open up the possibility for a new paradigm in skyrmionics research.

The discovery of novel spin objects with arbitrary topological charge promises to contribute to advances in fundamental and applied research, particularly through their application in information storage devices.

Magnetic skyrmions are localized, stable topological magnetic spin textures resembling a tornado-like whirl in a magnetic material. They can be very small, with diameters in the nanometer range, and behave as particles that can be moved, created, and annihilated, which makes them suitable for ‘abacus’-type applications in information storage and logic devices.

A team of biochemists at the Medical Research Council Laboratory of Molecular Biology at Cambridge has developed a new method to incorporate structurally unusual amino acids into proteins by using bacteria. The method is described in the journal Nature.

Prior research has shown that DNA codes for just 20 amino acids, the building blocks for making all the proteins used by living creatures. These are known as alpha amino acids. Prior research has also suggested that beneficial compounds could be created with a method to create proteins using beta amino acids. Researchers have suggested that applications could include the development of new kinds of medicines and possibly novel catalysts for manufacturing processes.

Such proteins have been engineered via syntheses in the lab. but scientists would prefer a more natural approach, which would be both cheaper and more efficient. This means that a technique is required to get a living cell to generate a desired protein using a beta amino acid.

Deepseek-coder: when the large language model meets programming — the rise of code intelligence.

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Tisch Cancer Institute researchers have discovered that a certain type of chemotherapy improves the immune system’s ability to fight off bladder cancer, particularly when combined with immunotherapy.

These findings, published in Cell Reports Medicine, may explain why the approach, cisplatin chemotherapy, can lead to a cure in a small subset of patients with metastatic, or advanced, bladder cancer. Researchers also believe that their findings could explain why clinical trials combining another type of chemotherapy, carboplatin-based chemo, with immunotherapy have not been successful but others that use cisplatin with immunotherapy are successful.

“We have known for decades that cisplatin works better than carboplatin in bladder cancer, however, the mechanisms underlying those clinical observations have remained elusive until now,” said the study’s lead author Matthew Galsky, M.D., Co-Director of the Center of Excellence for Bladder Cancer at The Tisch Cancer Institute at Mount Sinai.

Compared to robots, human bodies are flexible, capable of fine movements, and can convert energy efficiently into movement. Drawing inspiration from human gait, researchers from Japan crafted a two-legged biohybrid robot by combining muscle tissues and artificial materials. Published on January 26 in the journal Matter, this method allows the robot to walk and pivot.

“Research on biohybrid robots, which are a fusion of biology and mechanics, is recently attracting attention as a new field of robotics featuring biological function,” says corresponding author Shoji Takeuchi of the University of Tokyo, Japan. “Using muscle as actuators allows us to build a compact robot and achieve efficient, silent movements with a soft touch.”

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Some EV owners in the Sunshine State are reporting having to buy tires after just 5,000 to 7,000 miles of driving.

Mapping connectome hubs in the brain.

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The Big Ring in the Sky is 9.2 billion light-years from Earth. It has a diameter of about 1.3 billion light-years, and a circumference of about 4 billion light-years. If we could step outside and see it directly, the diameter of the Big Ring would need about 15 full moons to cover it.

It is the second ultra-large structure discovered by University of Central Lancashire (UCLan) Ph.D. student Alexia Lopez who, two years ago, also discovered the Giant Arc in the Sky. Remarkably, the Big Ring and the Giant Arc, which is 3.3 billion light-years across, are in the same cosmological neighborhood—they are seen at the same distance, at the same cosmic time, and are only 12 degrees apart in the sky.

Alexia said, Neither of these two ultra-large structures is easy to explain in our current understanding of the universe. And their ultra-large sizes, distinctive shapes, and cosmological proximity must surely be telling us something important—but what exactly?