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Can psychedelic mushrooms turn back the clock? Study suggests psilocybin preserves telomere length

A compound found in psychedelic mushrooms may have antiaging properties. Researchers at Baylor College of Medicine have found that psilocybin, the active compound in psychedelic mushrooms, may extend both cellular and organismal lifespans.

The findings, published in the journal npj Aging, show that psilocybin reduced multiple hallmarks of aging in cells while also improving survival in aged mice.

“There have been a number of clinical studies that have explored the therapeutic potential of psilocybin in psychiatric conditions such as depression and anxiety; however, few studies have evaluated its impacts outside the brain,” said Dr. Louise Hecker, associate professor of medicine— at Baylor and senior author of the study.

AI reveals astrocytes play a ‘starring’ role in dynamic brain function

Long overlooked and underestimated, glial cells—non-neuronal cells that support, protect and communicate with neurons—are finally stepping into the neuroscience spotlight. A new Florida Atlantic University study highlights the surprising influence of a particular glial cell, revealing that it plays a much more active and dynamic role in brain function than previously thought.

Using sophisticated computational modeling and , researchers discovered how astrocytes, a “star” shaped glial cell, subtly—but significantly—modulate communication between neurons, especially during highly coordinated, synchronous brain activity.

“Clearly, are significantly implicated in several brain functions, making identifying their presence among neurons an appealing and important problem,” said Rodrigo Pena, Ph.D., senior author, an assistant professor of biological sciences within FAU’s Charles E. Schmidt College of Science on the John D. MacArthur Campus in Jupiter, and a member of the FAU Stiles-Nicholson Brain Institute.

Treating postoperative delirium as preventable ‘acute brain failure’: Low-cost interventions could have major impact

A new large-scale study spotlights postoperative delirium as a preventable and high-impact complication which is driven by patient frailty and surgical stress—and one that can be addressed through low-cost, evidence-based interventions.

The findings, which appear in JAMA Network Open, provide a call to action for clinicians, health systems, patients, and families to prioritize brain health throughout perioperative care.

“Postoperative delirium isn’t a minor complication—it’s analogous to acute brain failure, a medical emergency that should be recognized and addressed,” said Laurent Glance, MD, a professor of Anesthesiology and Perioperative Medicine at the University of Rochester Medical Center (URMC) and senior author of the study.

Ice in Space Could Do Something We Thought Was Impossible

Water frozen in the darkness of space doesn’t appear to behave the way we thought.

A new research effort using computer simulations and experiments to explore the most common form water takes in the Universe has found that it is not as structureless as scientists had thought. Rather, repeating patterns – otherwise known as crystals – just a few nanometers across are likely embedded in an otherwise frozen jumble of molecules.

Since scientists had thought space too cold for ice crystals to have the energy to form, this discovery comes as a big surprise.

Divide-and-conquer strategy with engineered ossification center organoids for rapid bone healing through developmental cell recruitment

Critical-sized bone defects are a clinical challenge, with long-term recovery often leading to delayed union or nonunion. Here, Zhang et al. report an engineered ossification center-like organoid which recruits Krt8+ skeletal stem cells and reduces Has1+ fibrotic cells, mimicking developmental bone formation for regeneration of critical-sized bone defects.