Lifeboat Foundation

Research targeting the insulin-inhibitory receptor, or inceptor, unveils promising avenues for beta cell protection, offering hope for causal diabetes therapy.

A novel study in mice with diet-induced obesity demonstrates that the knock-out of inceptor enhances glucose regulation, prompting its further exploration as a drug target for type 2 diabetes treatment.

These findings, led by Helmholtz Munich in collaboration with the German Center for Diabetes Research, the Technical University of Munich, and the Ludwig-Maximilians-University Munich, drive advancements in diabetes research. They have been published in Nature Metabolism.

Scientists at UC San Francisco may have discovered a new way to test for autism by measuring how children’s eyes move when they turn their heads. They found that kids who carry a variant of a gene that is associated with severe autism are hypersensitive to this motion.

The gene, SCN2A, makes an ion channel that is found throughout the brain, including the region that coordinates movement, called the cerebellum. Ion channels allow electrical charges in and out of cells and are fundamental to how they function. Several variants of this gene are also associated with severe epilepsy and intellectual disability.

The researchers found that children with these variants have an unusual form of the reflex that stabilizes the gaze while the head is moving, called the vestibulo-ocular reflex (VOR). In children with autism, it seems to go overboard, and this can be measured with a simple eye-tracking device.

https://www.news-medical.net/news/20240228/ChatGPT-aids-in-d…osing.aspx Nature

ChatGPT-4 to identify drug repurposing candidates against Alzheimer’s disease (AD).

Last year, scientists discovered a mathematically perfect star system — and now, they’re looking into whether it might contain signs of alien tech.

Dubbed HD 110067, the star system located just 100 light-years from Earth has six exoplanets that are each perfectly spaced apart in the sort of mathematical harmony rarely seen in our chaotic Universe. In a paper published in the journal Nature last November, scientists listed off the astounding attributes of the system, which unfortunately did not include any planets in the so-called “habitable zone,” or distance from the orbit-inducing star that could support life as we know it here on Earth.

All the same, scientists aren’t done looking, and as radio astronomer and alien life-seeking expert Steve Croft of the University of Berkeley told Space.com, there’s no reason that advanced civilizations may not have visited HD 110,067 and potentially left some of their technology behind.

One major area of our lives that uses largely “hidden” AI is transportation. Millions of flights and train trips are coordinated by AI all over the world. These AI systems are meant to optimize schedules to reduce costs and maximize efficiency.

Artificial intelligence can also manage real-time road traffic by analyzing traffic patterns, volume and other factors, and then adjusting traffic lights and signals accordingly. Navigation apps like Google Maps also use AI optimization algorithms to find the best path in their navigation systems.

AI is also present in various everyday items. Robot vacuum cleaners use AI software to process all their sensor inputs and deftly navigate our homes.

Researchers can engineer cells to express new genes and produce specific proteins, giving the cells new parts to work with. But, it’s much harder to provide cells with instructions on how to organize and use those new parts. Now, new tools from University of Wisconsin–Madison researchers offer an innovative way around this problem.

Their research is published in the journal Cell.

Everything a cell does depends on how molecules are organized within the cell. Inside our cells—all cells—proteins and other molecules undergo organization and reorganization to carry out cellular function. Like a fleet of commuter trains moving at scheduled intervals along their different routes, proteins within a cell are organized in time and space to carry out complex but predictable functions.

Joscha Bach, Principal AI Engineer at Intel Labs Cognitive Computing group and member of our Scientific Advisory Board, and Rana Gujral, CEO at Behavioral Signals, on a FIRESIDE CHAT to talk about Artificial Consciousness and New Language Models: The changing fabric of our society, at DeepFest 2023.

Philosopher David Chalmers and neuroscientist Christof Koch made a bet in 1998 on a breakthrough in consciousness research within 25 years. Now the bet is settled – thanks to the journalist Per Snaprud, neuroscience editor at the Swedish popular science magazine Forskning \& Framsteg. Here’s a conversation that was held between the three at New York university on June 24:th 2023.