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Eating a high-fat diet containing a large amount of oleic acid—a type of fatty acid commonly found in olive oil—could drive obesity more than other types of dietary fats, according to a study published in the journal Cell Reports.

The study found that oleic acid, a monounsaturated fat associated with obesity, causes the body to make more fat cells. By boosting a signaling protein called AKT2 and reducing the activity of a regulating protein called LXR, high levels of oleic acid resulted in faster growth of the precursor cells that form new fat cells.

“We know that the types of fat that people eat have changed during the obesity epidemic. We wanted to know whether simply overeating a diet rich in fat causes obesity, or whether the composition of these fatty acids that make up the oils in the diet is important. Do specific fat molecules trigger responses in the cells?” said Michael Rudolph, Ph.D., assistant professor of biochemistry and physiology at the University of Oklahoma College of Medicine and member of OU Health Harold Hamm Diabetes Center.

Researchers at the U.S. Department of Energy (DOE)’s Oak Ridge National Laboratory (ORNL) have developed an innovative new technique using carbon nanofibers to enhance binding in carbon fiber and other fiber-reinforced polymer composites—an advance likely to improve structural materials for automobiles, airplanes and other applications that require lightweight and strong materials.

The results, published in the journal Advanced Functional Materials, show promise for making products that are stronger and more affordable, opening new options for U.S. manufacturers to use in applications such as energy and national security.

“The challenge of improving adhesion between carbon fibers and the that surrounds them has been a concern in industry for some time, and a lot of research has gone into different approaches,” said Sumit Gupta, the ORNL researcher who led the project. “What we found is that a hybrid technique using to create chemical and mechanical bonding yields excellent results.”

Macquarie University researchers have discovered a naturally occurring protein found in human cells plays a powerful role in repairing damaged DNA — the molecule that carries the genetic instructions for building and maintaining living things.

The discovery, published in the journal Ageing Cell, could hold the key to developing therapies for devastating age-related diseases such as motor neuron disease (MND), Alzheimer’s disease, and Parkinson’s disease.

Hope: Dr Sina Shadfar, pictured, and colleagues discovered a protein which they have shown for the first time acts like a ‘glue’, helping to repair broken DNA, which is widely accepted as one of the main contributors to ageing and the progression of age-related diseases.

The research, conducted by neurobiologist Dr Sina Shadfar and colleagues in the Motor Neuron Disease Research Centre, reveals a protein called protein disulphide isomerase (PDI) helps repair serious deoxyribonucleic acid (DNA) damage. This breakthrough opens new possibilities for therapies aimed at boosting the body’s ability to fix its own DNA — a process that becomes less efficient as we age.

From a data platform perspective, teams responsible for maintaining efficient, scalable infrastructure can benefit from M1’s support for structured function calling and its compatibility with automated pipelines. Its open-source nature allows teams to tailor performance to their stack without vendor lock-in.

Security leads may also find value in evaluating M1’s potential for secure, on-premises deployment of a high-capability model that doesn’t rely on transmitting sensitive data to third-party endpoints.

Taken together, MiniMax-M1 presents a flexible option for organizations looking to experiment with or scale up advanced AI capabilities while managing costs, staying within operational limits, and avoiding proprietary constraints.

At the core of this discovery, published in Science Advances, is barium titanate (BaTiO₃), a material known for its ability to convert light into electricity, though not very efficiently on its own.

The scientists found that by embedding thin layers of barium titanate between two other materials – strontium titanate and calcium titanate – they could create a structure that produces significantly more electricity than barium titanate alone, even while using less of it.

The improvement is striking. The layered structures generated up to 1,000 times more electricity than the same amount of standalone barium titanate. The researchers were also able to fine-tune this effect by adjusting the thickness of each layer, giving them control over the system’s performance.

Nature Communications paper.
Paper link: https://www.nature.com/articles/s41467-024-55157-2
PDF link: https://rdcu.be/d7B8C

This paper proposes a highly dexterous and compliant aerial continuum manipulator (Aerial Elephant Trunk). We have proposed the design, designed the shape estimation method, developed a feedback controller, and proposed a whole-body motion planning module such that the UAV and the continuum manipulator could carry out tasks as a whole.

AET can perform various challenging aerial manipulation tasks, including but not limited to:
1) grasping object of various sizes and shapes;
2) traversing constrained pipelines with various shapes;
3) aerial writing/painting;
4) performing manipulation in various complex environments.

#robot #drone #uav #airplane #robotics #artificialintelligence #technology #learning #deeplearning @UAVfutures @fpvdrones @meninododronefpv @Thedroneracingleague @RobotFutureAI

Although AI-based restoration methods can indeed bring new life to damaged paintings, the end result is typically a digital copy of the original painting. By contrast, a new MIT technique applies reversible repairs to the physical painting itself, in the form of a removable mask.

The process was developed by mechanical engineering graduate student Alex Kachkine, who restores paintings via traditional hand-painting techniques as a hobby.

He realized that many galleries have a number of paintings which never get displayed, because they require restoration that would take too long – and thus be too expensive – to perform by hand. Utilizing his method, however, restoration times could be reduced from years, months or weeks down to a matter of hours.