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►Reddit AMA: https://www.reddit.com/r/Futurology/comments/5hfmsl/cellage_…ells_with/


Our society has never aged more rapidly – one of the most visible symptoms of the changing demographics is the exponential increase in the incidence of age-related diseases, including cancer, cardiovascular diseases and osteoarthritis. Not only does aging have a negative effect on the quality of life among the elderly but it also causes a significant financial strain on both private and public sectors. As the proportion of older people is increasing so is health care spending. According to a WHO analysis, the annual number of new cancer cases is projected to rise to 17 million by 2020, and reach 27 million by 2030. Similar trends are clearly visible in other age-related diseases such as cardiovascular disease. Few effective treatments addressing these challenges are currently available and most of them focus on a single disease rather than adopting a more holistic approach to aging.

Recently a new approach which has the potential of significantly alleviating these problems has been validated by a number of in vivo and in vitro studies. It has been demonstrated that senescent cells (cells which have ceased to replicate due to stress or replicative capacity exhaustion) are linked to many age-related diseases. Furthermore, removing senescent cells from mice has been recently shown to drastically increase mouse healthspan (a period of life free of serious diseases).

Here at CellAge we are working hard to help translate these findings into humans!

CellAge, together with a leading synthetic biology partner, Synpromics, is going to develop synthetic promoters which are specific to senescent cells (SeneSENSE), as promoters that are currently being used to track senescent cells are simply not good enough to be used in therapies. The most prominently used p16 gene promoter has a number of limitations, for example. As our primary mission is to expand the interface between synthetic biology and aging research as well as drive translational research forward, we will offer senescence reporter assay to academics for free. We predict that in the very near future this assay will be also used as a quality control step in the cell therapy manufacturing process to make cell therapies safer!

Sweden is beginning to look at doing away with physical money in favor of a completely digital currency given that the amount of hard cash and coin in circulation has already decreased by 40 percent. While Sweden’s economy is better equipped to handle such a change, other countries do not share the same ability in infrastructure, and many would be resistant to the increased transparency of digital currency.

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Here’s my take on why the overpopulation objection to rejuvenation is morally unacceptable.


In this article, I’ll try to show that the overpopulation objection against rejuvenation is morally deplorable. For this purpose, whether or not the world is overpopulated or might be such in the future doesn’t matter. I’ll deal with facts and data in the two other articles dedicated to this objection; for now, all I want is getting to the conclusion that not developing rejuvenation for the sake of avoiding overpopulation is morally unacceptable (especially when considering the obvious and ethically more sound alternative), and thus overpopulation doesn’t constitute a valid objection to rejuvenation.

I’ll start with an example. Imagine there’s a family of two parents and three children. They’re not doing too well financially, and they live packed in a tiny apartment with no chances of moving somewhere larger. Clearly they cannot afford having more children, but they would really like having more anyway. What should they do?

The only reasonable answer is that they should not have any more children until they can afford having them. Throwing away the old ones for the sake of some other child to be even conceived yet would be nothing short of sheer madness.

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Husar, a 38-year-old telecom salesman, had spent most of his life eating the sort of Eastern European fare typical of his native Ukraine: lots of meat, potatoes, salt and saturated fats. DNA Lifestyle Coach suggested his body might appreciate a more Mediterranean diet instead.


Recently, Vitaliy Husar received results from a DNA screening that changed his life. It wasn’t a gene that suggested a high likelihood of cancer or a shocking revelation about his family tree. It was his diet. It was all wrong.

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We tend to think people who are insanely smart breeze through life without encountering any problems at all. They get the best grades in school, they graduate at the top of their class, and they usually land high-paying jobs. But being intelligent isn’t all it’s cracked up to be. Here are some of the signs that you or someone you know is highly intelligent.

Technology can be a catalyst for the creation or destruction of jobs, but historically, it has always ultimately created more opportunities for employment, not less. That’s not stopping many from speaking out against Amazon Go for its potential to increase unemployment, though.

According to Ford, however, the implementation of automation technology is inevitable because it has obvious advantages for both consumers and retailers. “I don’t think we can stop it,” he says. “It’s a part of capitalism, that there’s going to be this continuous drive for more efficiency.”

While many have been focusing on manufacturing and transportation as the industries that will be hardest hit by automation, Amazon Go is an example of how tech that exists right now could replace retail salespersons and cashiers, jobs that had the highest employment numbers in the U.S. in May 2015 according to the Bureau of Labor statistics.

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