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I think this could lead to immortality basically allowing for limited growth of dna structures but still offering unlimited lifespan. In short this also prevents cancer aswell.

Telomerase is a ribonuceloprotein complex responsible for maintaining telomeres and protecting chromosomal integrity. The human telomerase reverse transcriptase (hTERT) is expressed in ∼90% of cancer cells where it confers the capacity for limitless proliferation. Along with its established role in telomere lengthening, telomerase also serves noncanonical extra-telomeric roles in oncogenic signaling, resistance to apoptosis, and enhanced DNA damage response. We report a new class of natural-product-inspired covalent inhibitors of telomerase that target the catalytic active site.

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This also an amazing supplement that also exists in all foods called nad plus that stops age related symptoms.

Nicotine, a metabolite of the NAD+ metabolic pathway, has been found to possess anti-inflammatory and neuroprotective properties, yet the underlying molecular mechanisms remained unknown. Here, the authors show that low-dose nicotine promotes SIRT1 deacetylation of NAMPT and enhanced NAMPT activity which boosts NAD generation and improves age related symptoms.

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Though hardly conclusive, this study strongly suggests that boosting NAD+ levels in humans could have incredible health benefits.

That’s where Basis comes in.

Created by Elysium Health, Basis is a proprietary formulation of crystalline nicotinamide riboside and pterostilbene, which the human body converts into NAD+. In a double-blind, randomized, placebo-controlled clinical trial, it was demonstrated that, on average, Basis increases NAD+ levels by 40 percent. These elevated NAD+ levels won’t necessarily stop the aging process. But they will certainly maximize cellular health, boost energy, and support healthy sleep. This in turn should allow people who are in good health to maintain it longer, and thus age better.

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Ronald Rael and Virginia San Fratello may have met as graduate students in architecture at Columbia University, but it quickly became clear that “architecture” would prove an inadequate term to describe their eclectic body of work.

As the pair started working together in 2002, they became increasingly aware that “sometimes the forces that enable architecture, chiefly capitalism, can corrupt the architect’s social agenda,” Rael says. “This became the impetus to rethink how and why architecture should be created.”

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An international team of astronomers has uncovered the formation history of young star clusters, many of which are visible to the naked eye at night.

This remarkable research reveals that most nearby young star clusters belong to only three families, each originating from very massive star-forming regions.

The findings offer new insights into the effects of supernovae on the formation of giant gas structures in galaxies like our Milky Way.

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Join host Nick Tucker and team for the first ever Hard Reset Podcast episode on vertical farming. We’re diving deeper on the technology and ideas featured in our vertical farming video episode, sharing bonus info that never made it to the final cut, and responding to some of the most popular (and meanest) comments.

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Researchers at the Hebrew University of Jerusalem say they have developed a way to accurately predict the behavior of cancer cells, which will advance diagnosis and treatment of the disease.

The new diagnostic tool uses AI machine learning combined with nanoinformatics (observing nanomaterials) to classify cancer cell behavior in individual patient biopsies, potentially paving the way for personalized monitoring of the progression of the disease and the impact of treatments.

The study was led by Hebrew University doctoral student Yoel Goldstein and Prof. Ofra Benny from its School of Pharmacy in the Faculty of Medicine, working with Prof. Tommy Kaplan, the head of the Department of Computational Biology at the School of Engineering and Computer Science.

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