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Mar 11, 2024

Chinese researchers turn diamonds into good conductors of electricity

Posted by in category: materials

Scientists used graphene, another form of carbon, but a good conductor of electricity to transform their new diamonds into conductors.

Mar 11, 2024

Protein ‘brake’ could help develop new cancer treatments

Posted by in category: biotech/medical

Some cancerous tumors hijack proteins that act as “brakes” on our immune system and use them to form a sort of shield against immune recognition. Immunotherapy treatments have been created that turn off these “brakes” and allow our body to attack foreign-looking cancer cells.

Mar 11, 2024

A fresh approach to quantum computers based on atoms and photons

Posted by in categories: computing, particle physics, quantum physics

From the article:

“Somewhere between one and ten million qubits are needed for a fault-tolerant quantum computer, whereas IBM has only just realized a 1,200-qubit computer,” says Aoki.


While this approach isn’t limited to any specific platform for quantum computers, it does lend itself to trapped ions and neutral atoms since they don’t need to be cooled to cryogenic temperatures, which makes them much easier to connect.

Continue reading “A fresh approach to quantum computers based on atoms and photons” »

Mar 11, 2024

The Quest to Give AI Chatbots a Hand—and an Arm

Posted by in category: robotics/AI

Robotics startup Covariant is experimenting with a ChatGPT-style chatbot that can control a robotic arm, as a way to create machines that can be more helpful in the physical world.

Mar 11, 2024

Daratumumab Plus Standard Therapy for Multiple Myeloma

Posted by in category: biotech/medical

People in the daratumumab group who stayed MRD negative for at least a year were able to stop taking daratumumab as maintenance therapy and remained cancer free. That’s important, Dr. Sonneveld said, because taking fewer drugs long-term for maintenance therapy often translates to a better well-being and quality of life.

Adding daratumumab to the standard treatment resulted in a nearly 60% drop in the risk of cancer progression or death (hazard ratio of 0.42), the researchers determined.

The magnitude of that change is “unprecedented in these kinds of phase 3 trials [for] multiple myeloma,” Dr. Sonneveld said.

Mar 11, 2024

Clinical case: Breast cancer development after prophylactic subcutaneous mastectomy

Posted by in category: biotech/medical

This article describes a clinical case of breast cancer, its diagnosis, possible prophylaxis, causes, and anatomy. Click now.

Mar 11, 2024

Checkpoint Dimer May Toggle between Anticancer and Antiautoimmune Action

Posted by in category: biotech/medical

The authors cited results from a recent Phase II clinical trial reporting that Peresolimab, a PD-1 agonist monoclonal antibody, was effective in treating rheumatoid arthritis, but that the mechanism whereby peresolimab acts as an agonist was not reported. “Our characterization of PD-1 TMD dimerization may help inform evolving strategies for developing both agonists and antagonists,” they stated.

Co-senior investigator and cancer immunologist Jun Wang, PhD, an assistant professor in the Department of Pathology at NYU Grossman and Perlmutter, added, “Our findings offer new insights into the molecular workings of the PD-1 immune cell protein that have proven pivotal to the development of the current generation of anticancer immunotherapies, and which are proving essential in the design and developing of the next generation of immunotherapies for autoimmune diseases.”

Among the study’s findings was that a single change in the amino acid structure of the transmembrane segment can act to either enhance or diminish the inhibitory function of PD-1 in immune responses. The team plans further investigations of PD-1 inhibitors and agonists to see if they can tailor what they say are more effective, “rationally designed” therapies for both cancer and autoimmune disorders. Concluding on their findings in their paper, the team wrote, “In this study, we show that PD-1 and its ligands form dimers as a consequence of transmembrane domain (TMD) interactions and that propensity for dimerization correlates with PD-1 ability to inhibit immune responses, antitumor immunity, cytotoxic T cell function, and autoimmune tissue destruction. These observations contribute to our understanding of the PD-1 axis and how it can potentially be manipulated for improved treatment of cancer and autoimmune diseases.”

Mar 11, 2024

Reconfigurable electronics: More functionality on less chip area

Posted by in categories: computing, electronics

Even the most complicated data processing on a computer can be broken down into small, simple logical steps: You can add individual bits together, you can reverse logical states, you can use combinations such as “AND” or “OR.” Such operations are realized on the computer by very specific sets of transistors. These sets then form larger circuit blocks that carry out more complex data manipulations.

Mar 11, 2024

Google prepares to release built-in satellite messaging feature, could be included in Android 15

Posted by in category: mobile phones

An alternative satellite messaging service was spotted in the latest beta version of Android 14, and it may be included in Android 15.

According to an Android Authority report, the Android beta now shows a new “Satellite Messaging” page that states users can “send and receive text messages by satellite as part of an eligible account.” Next is a button that users can tap once it arrives to add the feature to their mobile plan.

In terms of functionality, users can take advantage of it when they don’t have a cellular or Wi-Fi connection. In addition to emergency services, users can contact anyone they know. It is claimed that the antennas would support 2 to 4MB of data transmission per cell area.

Mar 11, 2024

New type of tunable filter reveals the potential for terahertz wireless communications

Posted by in category: futurism

Electromagnetic waves in the terahertz frequency range offer many advantages for communications and advanced applications in scanning and imaging, but realizing their potential poses challenges. Researchers at Tohoku University have addressed one of the key challenges by developing a new type of tunable filter for signals in the terahertz wave band. They published their work in the journal Optics Letters.