Scientists have created a complete E. coli genome with an altered “genetic dictionary,” a significant step toward the project of synthetic life.
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The next step in human evolution is closer than you think.
3D Map of the cell-building protein tied to cancer.
The unprecedented view of the protein doublecortin kinase like domain 1 (DCLK1) could provide clues to how it contributes to cancer formation and progression.
DCLK1 is a protein that assembles scaffolds within cells called microtubules. These rope-like structures give cells shape, enable movement and cell division, and are crucial in enabling the growth and spread of cancer cells. More than one in 10 stomach cancers have defective forms of DCLK1, which have also been found in kidney, rectal and pancreatic cancers.
Walter and Eliza Hall Institute scientists Dr Onisha Patel and Dr Isabelle Lucet used the Australian Synchrotron to reveal the three-dimensional structure of a part of DCLK1 known as the ‘kinase domain’.
The 1st Church of Singularity — guess Ray is preaching again.
By Jodi Schiller
For those of us working in virtual and augmented reality, our days are spent thinking of better and better ways to create more lifelike virtual worlds. It’s easy for us to believe that one day we will be living in a sim indecipherable from “base” reality — or even more likely, that we’re already living in one.
A collaboration of physicists and a mathematician has made a significant step toward unifying general relativity and quantum mechanics by explaining how spacetime emerges from quantum entanglement in a more fundamental theory. The paper announcing the discovery by Hirosi Ooguri, a Principal Investigator at the University of Tokyo’s Kavli IPMU, with Caltech mathematician Matilde Marcolli and graduate students Jennifer Lin and Bogdan Stoica, will be published in Physical Review Letters as an Editors’ Suggestion “for the potential interest in the results presented and on the success of the paper in communicating its message, in particular to readers from other fields.”
Physicists and mathematicians have long sought a Theory of Everything (ToE) that unifies general relativity and quantum mechanics. General relativity explains gravity and large-scale phenomena such as the dynamics of stars and galaxies in the universe, while quantum mechanics explains microscopic phenomena from the subatomic to molecular scales.
The holographic principle is widely regarded as an essential feature of a successful Theory of Everything. The holographic principle states that gravity in a three-dimensional volume can be described by quantum mechanics on a two-dimensional surface surrounding the volume. In particular, the three dimensions of the volume should emerge from the two dimensions of the surface. However, understanding the precise mechanics for the emergence of the volume from the surface has been elusive.
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