Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 11170

The biotech battle between China and the US has begun as we predicated when we announced the first CRISPR deployment in humans last month. The US has upped the ante and is taking a step further in the race for the biotech crown. All great news for us as the more competition the faster progress will move so let’s hope there is a fierce battle for biotech coming.

In 2015, a little girl called Layla was treated with gene-edited immune cells that eliminated all signs of the leukemia that was killing her. Layla’s treatment was a one-off, but by the end of 2017, the technique could have saved dozens of lives.

It took many years to develop the gene-editing tool that saved Layla, but thanks to a revolutionary method known as CRISPR, this can now be done in just weeks.

In fact, CRISPR works so well that the first human trial involving the method has already begun. In China, it is being used to disable a gene called PD-1 in immune cells taken from individuals with cancer. The edited cells are then injected back into each person’s body.

Continue reading “CRISPR gene editing human trials in China and US offer hope for countless lives” | >

Google Tech Talk with the SENS Research Foundation!

Commentary about our recent Google Tech Talk about the MitoSENS project from FightAging!

“As the clock ticks on this year’s SENS rejuvenation research fundraiser — less than two weeks to go now, and plenty left in the matching fund for new donations — it is good to be reminded of the progress that the SENS Research Foundation has accomplished with the charitable funding of recent years. With that in mind, today I’ll point you to a recent Google Tech Talk that provides a layperson’s introduction to one of the projects that our community has funded, fixing the problem of mitochondrial damage in aging. The point of the SENS (Strategies for Engineered Negligible Senescence) research programs is to accelerate progress towards specific forms of therapy that can bring aging under medical control.”

Read more

In a technological tour de force, scientists have developed a new way to probe antimatter.

For the first time, researchers were able to zap antimatter atoms with a laser, then precisely measure the light let off by these strange anti-atoms. By comparing the light from anti-atoms with the light from regular atoms, they hope to answer one of the big mysteries of our universe: Why, in the early universe, did antimatter lose out to regular old matter?

“This represents a historic point in the decades-long efforts to create antimatter and compare its properties to those of matter,” says Alan Kostelecky, a theoretical physicist at Indiana University.

Read more

Slight variations in the moon’s gravitational tug have hinted that kilometers-wide caverns lurk beneath the lunar surface. Like the lava tubes of Hawaii and Iceland, these structures probably formed when underground rivers of molten rock ran dry, leaving behind a cylindrical channel. On Earth, such structures max out at around 30 meters across, but the gravitational data suggest that the moon’s tubes are vastly wider.

Other satellites had found the openings of large lunar lava tubes and caves.

  • The Lunar Reconnaissance Orbiter has now imaged over 200 pits that show the signature of being skylights into subsurface voids or caverns, ranging in diameter from about 16 feet (5 meters) to more than 2,950 feet (900 m), although some of these are likely to be post-flow features rather than volcanic skylights.

Read more

This cartoon depicts turning back the aging clock through cellular regeneration of progeria mice (credit: Juan Carlos Izpisua Belmonte Lab/Salk Institute)

Salk Institute scientists have extended the average lifespan of live mice by 30 percent, according to a study published December 15 in Cell. They did that by rolling back the “aging clock” to younger years, using cellular reprogramming.

The finding suggests that aging is reversible by winding back an animal’s biological clock to a more youthful state and that lifespan can be extended. While the research does not yet apply directly to humans, it promises to lead to improved understanding of human aging and the possibility of rejuvenating human tissues.

Read more

Waymo, the newly-minted Alphabet company that was previously Google’s self-driving car project, has a new addition to its vehicle fleet: 100 Chrysler Pacifica hybrid minivans, which were produced by Fiat Chrysler specifically for the purpose of making them fully autonomous using Waymo’s tech, onboard computer power, sensors and telematics. The 100 new cars will join Waymo’s other self-driving vehicles in active service on public roads for more testing starting early next year.

These vehicles were created through a close partnership between Waymo and FCA that actually saw engineering teams from both companies co-located at a Michigan engineering site, and testing of tech through the development process happened both in Chelsea, Michigan, and Yucca, Arizona on the FCA side, and at Waymo’s own test facilities in California.

While the Chrysler Pacificas used are based on the 2017 production model that consumers can buy, changes were made to the vehicles’ electrical, powertrain and structural systems, as well as to the vehicle chassis itself, in order to make them better suited for using Waymo’s tech. This results in a much tighter integration than if the Alphabet company had just purchased Chrysler vehicles off the line and done their own aftermarket modifications on stock vehicles. Still, from project outset to these being ready to enter service took only six months, according to FCA.

Read more