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Japanese automaker Toyota is serious about perfecting hydrogen fuel cell technology to power its vehicles, and it’s scheduled an initial feasibility study operations for its zero-emissions heavy-duty truck a little over a week from today. A concept version of a truck running Toyota’s specialized hydrogen fuel cell system designed for heavy-hauling use will be moving goods from select terminals at the Port of LA and Long Beach to nearby warehouses and rail yards beginning on October 23.

“If you see a big-rig driving around the Ports of Los Angeles and Long Beach that seems oddly quiet and quick, do not be alarmed! It’s just the future,” Toyota wrote in a press release. The company expects the daily runs to cover some 322 kilometers (200 miles) to test the fuel cell system’s duty-cycle capabilities. Afterwards, longer trips could be introduced.

Image credit: Toyota.

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Second article (#2 of 3) in three part stem cell series.


Summary: Stem cell decline leads to disease, gradual organ failure, and death. Learn what causes it and how researchers are trying to reverse stem cell decline. Part one of a two-part series.

Are stem cells the fountain of youth?

Recent discoveries suggest that stem cells may be able to regenerate most of our organs in the near future. Using regenerative medicine, death and disability from organ failure will soon be a relic of the past. Gone too will be the failures associated with organ transplantation. Using stem cell therapy, our declining immune systems will be restored, no longer compromised by old age. Finally, stem cells can minimize the dysfunction and mortality associated with infectious diseases.

First article (#1 of 3) in three part stem cell series.


Summary: A brief tutorial on the science behind stem cell therapy.

Doctors already use stem cells to treat blood diseases, a cell-based therapy that has saved the lives of thousands of children with leukemia. Additionally, physicians used stem cells to successfully treat some types of bone, skin, and eye injuries and diseases. The potential of stem cell therapies is enormous, and some researchers feel that we will be able to regrow organs in the near future.

Our Natural Stem Cells

Cellular Garb-aging is the build-up of junk inside the cells that naturally occurs during aging. This article says why it happens.


To maintain protein homeostasis, and prevent garb-aging, the cell uses molecular chaperones, which help assemble and disassemble proteins. Chaperonins are a special class of chaperones that provide favorable conditions for the correct folding of other proteins, thus preventing aggregation. Chaperonins prevent the misfolding of proteins, which prevents conditions such as Mad Cow Disease. Sometimes, chaperonin proteins may also tag misfolded proteins to be degraded. When properly tagged, other processes can recognize the damaged or misfolded proteins and ‘take out the trash.’

Think of it as garb-aging removal.

Aging Leads to Cellular Garb-Aging

Researchers have discovered why inflammaging occurs and are working on new treatments. Inflammaging is new medical term for “the chronic inflammation brought on by old age.”


Summary: Inflammaging is a low-grade inflammation brought on by old age. It accelerates the aging process and worsens diseases like cancer and heart disease. Because inflammaging accelerates aging, geroscientists are perfecting a few cures for the condition.

As we age, most of us tend to develop a low-grade chronic inflammation that causes disease and damage throughout the body. Because this low-level inflammation typically accompanies aging, scientists have nicknamed it ‘inflammaging.’ Most geroscientists implicate inflammaging as the cause of many of age-related diseases including diabetes, heart disease, cancer, and dementia. These chronic diseases accelerate aging and shorten our lives.

There is good news, however. Geroscientists feel that reducing inflammaging will eliminate or reduce these diseases. In fact, these anti-aging scientists have developed several potential remedies to solve the problem.

Does an out of whack microbiome cause inflammaging?


Does our microbiome cause inflammaging, the low-level chronic inflammation that plagues our bodies as we get older? A new research paper examines the question, and their findings just might surprise you.

Many people still regard bacteria and other microorganisms as mere disease-causing germs. However, it’s a lot more complicated than that. In fact, it has become increasingly clear that a healthy human body is teeming with microbes, which play a role in our immune system. We are not just an organism; we are a super-organism and the millions of microbes both within and without our bodies.

The Microbiome and Inflammaging

The number of people who believe—based on data, not faith—that humans can become (almost) immortal is growing, and includes the likes of scientists, billionaires, engineers and billionaire-engineers. For instance, investor Peter Thiel has donated to the anti-ageing cause, in addition to the $500,000 (around ₹3.2 crore) Palo Alto Longevity Prize for anyone who can radically extend the life of a mammal. Larry Ellison, the co-founder of Oracle, too has donated $335 million to scientists studying ageing before he decided to redirect his foundation’s grants toward eliminating polio in 2013.


When, in the future, expensive baubles cease to hold the same novelty they do today, redefined concepts of luxury are what the super-rich can pick from.

By harichandan arakali forbes india staff